Effect of Disease Duration and Activity and the Treatment Process on Central Sensitization in Patients with Ankylosing Spondylitis

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dc.contributor.authorGuler, Emel
dc.contributor.authorDoğancı, Alper
dc.contributor.authorGültürk, Esra
dc.contributor.authorArtık, Hanzade Aybüke Ünal
dc.contributor.authorHizmetli, Sami
dc.date.accessioned2024-10-26T17:33:37Z
dc.date.available2024-10-26T17:33:37Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: Ankylosing spondylitis (AS) is a chronic inflammatory disease. Its main symptom is inflammatory low back pain. The presence of central sensitization (CS) in chronic pain conditions has been emphasized in several studies, but there are insufficient studies on AS patients. The aim of this study was to evaluate the relationship between disease activity in AS, the type of pain, and the presence of CS. Methods: Patients’ age, gender, body mass index, disease duration, drugs used in the treat ment, pain type and severity, presence of CS disease activity, and quality of life were evaluated. Results: Evaluation was made on 80 patients, comprising 49 (61.2%) females and 31 (38.8%) males. A statistical significance was found between the presence of CS and high scores of painDETECT, Bath Ankylosing Spondylitis Disease Activity Index, Numerical Rating Scale for pain, Ankylosing Spondylitis Disease Activity Index-sedimentation, Ankylosing Spondylitis Quality of Life Index, low Short-Form-12 (SF-12) physical score (***p<0.001), low SF-12 men tal score (**p<0.01), and increased age (* p<0.05). Conclusion: The results of this study demonstrated that as CS was present in the majority of AS patients, multidirectional evaluation of these patients is required, and in treatment approaches, evaluation is important in respect of treatments for CS in addition to the sup pression of inflammation.
dc.identifier.doi10.14744/scie.2022.27880
dc.identifier.endpage236
dc.identifier.issn2587-0998
dc.identifier.issn2587-1404
dc.identifier.issue3
dc.identifier.startpage231
dc.identifier.trdizinid1134942
dc.identifier.urihttps://doi.org/10.14744/scie.2022.27880
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1134942
dc.identifier.urihttps://hdl.handle.net/20.500.12418/23222
dc.identifier.volume33
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofSouthern Clinics of Istanbul Eurasia
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEffect of Disease Duration and Activity and the Treatment Process on Central Sensitization in Patients with Ankylosing Spondylitis
dc.typeArticle

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