Metabolome in urology practices: Signatures in plasma and urine

Comparing the vast variation in biochemical processes seen in tumor cells with normal cells can be considered the initiation of metabolomics research, which is now used in different medical fields. Currently, there is an undisputed need for clinically relevant biomarkers that can be used for the diagnosis and prognosis of urologic cancer types, e.g., prostate, bladder, and metabolomics can be considered promising at this stage. Novel and relevant biomarkers are required for specialized diagnosis, monitoring, and treatment of a particular disease, which would also contribute to the improvement, enhancement, and personalization of a designed therapy. While considerable progress has been made in determining important biomarkers, more challenges remain to be solved for the further integration of metabolomics into clinical practices. This chapter reviews relevant metabolomics research conducted in the field urology. © 2023 Nova Science Publishers, Inc. All rights reserved.