Introduction and overview of applications related to green solvents used in sample preparation

Sample preparation is critical to the entire analytical procedure because it enables precise and accurate analyte evaluation by removing matrix challenges. Traditional sample preparations are regarded as the costliest, most time-consuming, and most hazardous organic solvents. Using environmentally friendly solvents in analytical methods for sample preparation and following green analytical chemistry principles adds greatly to the advancement of green analytical approaches. Utilizing their solvation characteristics and greenness benefits, these sustainable natural solvents can be designed as potential extractant for their targeted applications, permitting efficient and safe sample preparation before instrumental evaluation. In this chapter, we offer a brief overview of recent developments in the prominent environmentally friendly solvents used in analytical methods. The amphiphilic solvents, supramolecular solvents, hydrophilicity switchable solvents, ionic liquids, and deep eutectic solvents were explained. as well as applications of green solvents, paired with different methods for extremely selective and sensitive assessment. Lastly, we examine potential prospects in this field. © 2025 Elsevier Inc. All rights reserved.