Screening of the antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of inula oculus-christi

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dc.contributor.authorBerk, Seyda
dc.contributor.authorTepe, Bektas
dc.contributor.authorArslan, Serdal
dc.date.accessioned2024-10-26T17:54:27Z
dc.date.available2024-10-26T17:54:27Z
dc.date.issued2011
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractIn this study, in vitro antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of Inula oculus-christi was firstly evaluated in addition to its total phenolic and flavonoid contents. Antioxidant activity was determined by five complementary test systems named as ?-carotene linoleic acid, 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH) free radical scavenging, reducing power, chelating effect and phosphomolibdenum methods. The extract exhibited remarkable activity potential in DPPH free radical scavenging system. Antimicrobial activity was determined by agar-well diffusion and minimum inhibitory concentration tests. In this case, Shigella dysanteriae, Staphylococcus aureus, Shigella boydii and Bacillus subtilis was found as the sensitive microorganisms. According to the electrophoretic pattern of pBR322 plasmid DNA after treatment with UV and H2O2, supercoiled DNA was successfully protected in the presence of 14.28 mg/ml or above the concentrations of the aqueous extract. ©2011 Academic Journals.
dc.identifier.endpage1702
dc.identifier.issn1996-0816
dc.identifier.issue14
dc.identifier.scopus2-s2.0-80054867302
dc.identifier.scopusqualityN/A
dc.identifier.startpage1695
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27218
dc.identifier.volume5
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofAfrican Journal of Pharmacy and Pharmacology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntimicrobial activity; Antioxidant activity; DNA damage protection; Inula oculus-christi
dc.titleScreening of the antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of inula oculus-christi
dc.typeArticle

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