Does the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?

Basit Öğe Kaydı
dc.contributor.authorDoğan, Mehtap
dc.contributor.authorDurmuş, Kasım
dc.contributor.authorHasbek, Zekiye
dc.contributor.authorAltuntaş, Emine Elif
dc.date.accessioned2024-10-26T17:51:39Z
dc.date.available2024-10-26T17:51:39Z
dc.date.issued2018
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: The objective of this study was to examine the effect of hypothyroidism on hearing function in patients surgically treated for differentiated thyroid cancer and subsequently experienced hypothyroidism during preparation for follow up I-131 scintigraphy scan by either recombinant human thyroid stimulating hormone (rhTSH) treatment or thyroid hormone withdrawal (THW). Methods: A total of 55 patients undergoing I-131 scintigraphy scan following surgeries for differentiated thyroid cancer were included in the study, including 25 patients prepared by administration of recombinant TSH (rhTSH Group) and 30 patients by thyroid hormone withdrawal (THW Group). Results: Air conduction thresholds at 1, 2 and 4 kHz for both ears were higher during hypothyroid period than during euthyroid period for patients in the THW group (p < 0.05) but not for patients in the rhTSH group. Conclusion: Sensorineural hearing loss was detected, especially at low frequencies, in patients with DTC after surgical treatment whose hormone replacement therapy was withdrawn but not in those receiving rhTSH. It is therefore preferred to use rhTSH when preparing for I-131 scintigraphy scan in patients at risk for hearing loss. © 2018 PLA General Hospital Department of Otolaryngology Head and Neck Surgery
dc.identifier.doi10.1016/j.joto.2017.10.001
dc.identifier.endpage24
dc.identifier.issn1672-2930
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85071354930
dc.identifier.scopusqualityQ2
dc.identifier.startpage20
dc.identifier.urihttps://doi.org/10.1016/j.joto.2017.10.001
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26359
dc.identifier.volume13
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPLA General Hospital Department of Otolaryngology Head and Neck Surgery
dc.relation.ispartofJournal of Otology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHearing loss; Radioiodine; Recombinant TSH; Thyroid hormone withdrawal
dc.titleDoes the use of recombinant TSH in preparation for I-131 scintigraphy scan affect hearing function?
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu