Frequency and predictors of hyperkalemia in the heart failure outpatient clinic

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dc.contributor.authorÖztekin, Gülsüm Meral Yılmaz
dc.contributor.authorGenç, Ahmet
dc.contributor.authorŞahin, Anıl
dc.contributor.authorÇağırcı, Göksel
dc.contributor.authorArslan, Şakir
dc.date.accessioned2024-10-26T17:41:00Z
dc.date.available2024-10-26T17:41:00Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAim: Hyperkalemia is a common and potentially life-threatening problem in heart failure (HF). In this study, we aimed to show the frequency of hyperkalemia and related factors in the HF outpatient clinic with real-life data.Methods: 1 146 patients monitored in the HF outpatient clinic with left ventricular ejection fraction ? 40% and potassium level ? 3.5 mmol/L were included.Results: The potassium value of the patients was median 4.6 mmol/L [IQR, 4.3-5]. It was evaluated in three groups as 3.5-5 mmol/L (normokalemia), 5.1-5.5 mmol/L (mild hyperkalemia) and ? 5.5 mmol/L (moderate to severe hyperkalemia), according to baseline potassium levels. Mild hyperkalemia was present in 14.5% and moderate to severe hyperkalemia was present in 7.1%. The potassium value was > 5 mmol/L in 21.6% of the patients. The estimated glomerular filtration rate (eGFR) (OR: 0.969, 95% CI: 0.961-0.976, p<0.001), angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACE-I/ARB) (OR: 1.697, 95% CI: 1.124-2.562, p=0.012), and mineralocorticoid receptor antagonists (MRA) (OR: 1.511, 95% CI: 1.066-2.142, p=0.02) were considered as independent factors for hyperkalemia.Conclusion: eGFR level, ACE-I/ARB, and MRA were associated with hyperkalemia in chronic HF in real-life data.
dc.identifier.doi10.30565/medalanya.1172354
dc.identifier.endpage284
dc.identifier.issn2587-0319
dc.identifier.issue3
dc.identifier.startpage278
dc.identifier.trdizinid1216477
dc.identifier.urihttps://doi.org/10.30565/medalanya.1172354
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1216477
dc.identifier.urihttps://hdl.handle.net/20.500.12418/24232
dc.identifier.volume6
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofActa Medica Alanya
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHyperkalemia
dc.subjectPotassium
dc.subjectHeart Failure
dc.subjectRenin-Angiotensin System.
dc.titleFrequency and predictors of hyperkalemia in the heart failure outpatient clinic
dc.typeArticle

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