Prognostic Factors in Stage III Non-Small-Cell Lung Cancer Patients
| dc.contributor.author | Urvay, Semiha Elmaci | |
| dc.contributor.author | Yucel, Birsen | |
| dc.contributor.author | Erdis, Eda | |
| dc.contributor.author | Turan, Nedim | |
| dc.date.accessioned | 2024-10-26T17:52:47Z | |
| dc.date.available | 2024-10-26T17:52:47Z | |
| dc.date.issued | 2016 | |
| dc.department | Sivas Cumhuriyet Üniversitesi | |
| dc.description.abstract | Aim: The objective of this study is to investigate prognostic factors affecting survival of patients undergoing concurrent or sequential chemoradiotherapy (CRT) for stage III non-small-cell lung cancer (NSCL). Methods and materials: We retrospectively reviewed the clinical records of 148 patients with advanced, inoperable stage III NSCLC, who were treated between 2007 and 2015. Results: The median survival was found to be 19 months and 3-year overall survival was 27%. Age (<65 vs >65 years, p=0.026), stage (IIIA vs IIIB, p=0.033), dose of radiotherapy (RT) (<60 vs >60 Gy, p=0.024) and treatment method (sequential chemotherapy+RT vs concurrent CRT, p=0.023) were found to be factors affecting survival in univariate analyses. Gender, histological subtype, weight loss during CRT, performance status, induction/consolidation chemotherapy and presence of comorbidities did not affect survival (p>0.050). Conclusion: Young age, stage IIIA, radiotherapy dose and concurrent chemoradiotherapy may positively affect survival in stage III NSCL cases. © 2016. All Rights Reserved. | |
| dc.identifier.doi | 10.22034/APJCP.2016.17.10.4693 | |
| dc.identifier.endpage | 4697 | |
| dc.identifier.issn | 1513-7368 | |
| dc.identifier.issue | 10 | |
| dc.identifier.scopus | 2-s2.0-85111782006 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 4693 | |
| dc.identifier.uri | https://doi.org/10.22034/APJCP.2016.17.10.4693 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12418/26508 | |
| dc.identifier.volume | 17 | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | Asian Pacific Organization for Cancer Prevention | |
| dc.relation.ispartof | Asian Pacific Journal of Cancer Prevention | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Non-small lung cancer; prognostic factors; survival | |
| dc.title | Prognostic Factors in Stage III Non-Small-Cell Lung Cancer Patients | |
| dc.type | Article |
