Evaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study

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dc.contributor.authorKıymaz, Yasemin Çakır
dc.contributor.authorKarakök, Taliha
dc.contributor.authorBüyükkörük, Merve
dc.contributor.authorManavlı, Barış
dc.contributor.authorBaysal, Cihad
dc.contributor.authorKaraşın, Muhammed Fatih
dc.contributor.authorIşık, Merve Türker
dc.date.accessioned2025-05-04T16:42:06Z
dc.date.available2025-05-04T16:42:06Z
dc.date.issued2025
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground: This study aimed to determine the frequency of compliance with surgical antimicrobial prophylaxis (SAP) in Turkey and to identify the causes for noncompliance. Methods: This multicenter, prospective, point prevalence study was conducted in 8 hospitals from different regions of Turkey. Patients over 18 years who underwent SAP in all hospital surgical units were included. The SAP compliance assessment was carried out under 5 headings: unnecessary prophylaxis, inappropriate drug choice, prolonged prophylaxis, inappropriate dose interval, and inappropriate dosage. Results: The study included 541 patients from 8 centers. About 52.7% (n = 285) were female and the median age was 54 years (min-max: 18-94). Orthopedics (23.7%) and general surgery (22.2%) were the most common specialties. SAP compliance was 14%. The specialty with the highest rate of inappropriate SAP was orthopedics (97%) and the lowest rate was in ophthalmology (25%). The most common causes of inappropriate SAP were prolonged prophylaxis (92.0%) and inappropriate dose interval (84.6%). Multivariate logistic regression analysis revealed that prolonged surgical time, American Society of Anaesthesiologists (ASA) score 3, and some specialties increased the risk of noncompliance with surgical prophylaxis. Conclusions: This study showed that SAP compliance is low in Turkey and that inappropriateness is caused mostly by prolonged and inappropriate antimicrobial use. © 2025 Association for Professionals in Infection Control and Epidemiology, Inc.
dc.identifier.doi10.1016/j.ajic.2025.01.014
dc.identifier.endpage558
dc.identifier.issn0196-6553
dc.identifier.issue5
dc.identifier.pmid39855272
dc.identifier.scopus2-s2.0-85216893561
dc.identifier.scopusqualityQ1
dc.identifier.startpage552
dc.identifier.urihttps://doi.org/10.1016/j.ajic.2025.01.014
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35067
dc.identifier.volume53
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Inc.
dc.relation.ispartofAmerican Journal of Infection Control
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250504
dc.subjectAntibiotic resistance
dc.subjectAntimicrobial stewardship
dc.subjectSurgical prophylaxis
dc.titleEvaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study
dc.typeArticle

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