The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection

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dc.contributor.authorYıldırım, Salih
dc.contributor.authorOrak, Yavuz
dc.contributor.authorMenencioğlu, Rukiye
dc.contributor.authorAltun, Ahmet
dc.contributor.authorOrak, Filiz
dc.contributor.authorDüger, Cevdet
dc.contributor.authorÖzpay, Esra
dc.date.accessioned2024-10-26T17:44:12Z
dc.date.available2024-10-26T17:44:12Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: Aim of study is to determine which antibiotic is started empirically in the ICU and to investigate whetherthe antibiotic started according to culture result was changed or not and the effect of this change on mortality, and toinvestigate the relationship between mortality and infection by determining whether enteral and parenterally fedpatients have attained sufficient calorie level.Method: After the approval of the local ethics committee, the files of 476 patients hospitalized in our hospital wereretrospectively reviewed. A total of 159 patients over 18 years of age who received mechanical ventilation therapy forat least 3 days were included in the study. Blood, urine and tracheal aspirate culture were determined. It wasrecorded whether antibiotics had changed according to the culture result. Nutritional patterns, number of feedingdays and basal caloric need were determined. It was investigated whether basal calorie need was met on 1, 3 and 5days. Factors affecting mortality were investigated.Results: Antibiotic exchange was significantly higher in the patients who died (P = 0.002). Mortality was higher inpatients who were unable to reach the target calorie (P = 0.01). Empirical changes in antibiotics (r: 0.174, P = 0.028),and culture positivity (r: 0.177, P = 0.026) were associated with mortality (r: 0.195, P = 0.014). In the subgroupanalysis, reproduction in tracheal aspirate culture was an important factor affecting mortality (r: 0.211 P: 0.008).Conclusions: The number of days of hospitalization, antibiotic change, culture positivity and inability to reach thetarget calories in nutrition are associated with mortality in the intensive care unit
dc.identifier.doi10.5798/dicletip.620514
dc.identifier.endpage498
dc.identifier.issn1300-2945
dc.identifier.issn1308-9889
dc.identifier.issue3
dc.identifier.startpage489
dc.identifier.trdizinid333329
dc.identifier.urihttps://doi.org/10.5798/dicletip.620514
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/333329
dc.identifier.urihttps://hdl.handle.net/20.500.12418/25161
dc.identifier.volume46
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofDicle Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGenel ve Dahili Tıp
dc.titleThe use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection
dc.typeArticle

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