The Effects of Magnetic Field on the Electrophysiological Parameters of Soleus Muscle in Streptozotocin-Induced Diabetic Rats

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dc.contributor.authorPelit, Aykut
dc.contributor.authorEmre, Mustafa
dc.contributor.authorDemirkazik, Ayse
dc.contributor.authorGunay, Ismail
dc.date.accessioned2024-10-26T18:09:02Z
dc.date.available2024-10-26T18:09:02Z
dc.date.issued2013
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose: To investigate the effects of magnetic field (MF) on the resting membrane potential and action potential parameters of the Soleus muscle preparations in streptozotocin (STZ) induced diabetic rats. Material and Methods: Forty male wistar rats were used in this study. The rats were divided into four groups; Group I (control), Group II (control with magnetic field), group III (diabetic), group IV (diabetic with magnetic field). The diabetes was induced by a single intravenous injection of STZ (45 mg/kg) in citrate buffer to the jugular vein under the ketamine and xylazine anesthetic combination. Resting membrane potential (RMP), muscle action potential (MAP), depolarization and half-repolarization time, MAP integral, depolarization and repolarization rates were recorded by means of the conventional microelectrode technique. Results: When group III and IV compared to group I, a significant decrease was found in the RMP (p<0.05). When control group compared to the other groups, MAP values found to be significant. When the depolarization time was compared there was a significant increase difference between group I and group III and group IV. Furthermore, half-repolarization time, MAP integral, depolarization and repolarization rates showed significant decrease results as occurred in MAP. Conclusion: MF increased the excitability of the cell membrane in RMP, which revealed that cell membrane had been more depolarized. It was assumed that this increase in depolarization may have been due to the changes in the conductivity of K+ and/or Cl-ion channels.
dc.identifier.endpage433
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue3
dc.identifier.startpage426
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29918
dc.identifier.volume38
dc.identifier.wosWOS:000216447600010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherCukurova Univ, Fac Medicine
dc.relation.ispartofCukurova Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSoleus muscle
dc.subjectstreptozotocin
dc.subjectresting membrane potential
dc.subjectaction potential
dc.subjectmagnetic field
dc.titleThe Effects of Magnetic Field on the Electrophysiological Parameters of Soleus Muscle in Streptozotocin-Induced Diabetic Rats
dc.typeArticle

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