Transient tachypnea of the newborn

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dc.contributor.authorKiliçbay, Fatih
dc.contributor.authorErdal, Hüseyin
dc.date.accessioned2024-10-26T17:54:39Z
dc.date.available2024-10-26T17:54:39Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractTransient tachypnea of the newborn is a physiological lung parenchyma disorder that is frequently seen in term and late preterm neonates. It occurs due to insufficient clearing of the fetal alveolar fluid. The clinical status is expected to return to normal within 48-72 hours. Although there is a limited effect of vaginal contractions and starling forces on the pathophysiology of the clearance of fetal lung fluid, the key mechanism is the osmotic gradient formed by the amiloride-sensitive sodium transport via EnaC from pulmonary epithelial cells, which facilitates the transepithelial movement of alveolar fluid from the pulmonary epithelium. Clinically, in patients with tachypnea there is observed to be groaning, flaring of the nostrils when breathing, intercostal and subcostal contractions, a need for oxygen, hypoxia, and occasionally, cyanosis. Oxygen is required in treatment and, in some cases, continuous positive airway pressure. © 2023 Nova Science Publishers, Inc. All rights reserved.
dc.identifier.endpage339
dc.identifier.isbn979-888697714-1
dc.identifier.isbn979-888697545-1
dc.identifier.scopus2-s2.0-85159890913
dc.identifier.startpage329
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27368
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherNova Science Publishers, Inc.
dc.relation.ispartofCurrent Topics in Perinatology and Neonatology
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEpithelial sodium channels; Newborn; Polymorphism; Transient tachypnea
dc.titleTransient tachypnea of the newborn
dc.typeBook Chapter

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