Systemic Immune Inflammation Index is a Novel Marker in Predicting the Presence and Severity of Isolated Coronary Artery Ectasia

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dc.contributor.authorDindas, Ferhat
dc.contributor.authorKoyun, Emin
dc.contributor.authorTurkyilmaz, Erdem
dc.contributor.authorAbacioglu, Ozge Ozcan
dc.contributor.authorYildirim, Arafat
dc.contributor.authorSahin, Anil
dc.contributor.authorDindar, Baris
dc.date.accessioned2024-10-26T17:52:56Z
dc.date.available2024-10-26T17:52:56Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground: The underlying pathology of isolated coronary artery ectasia (CE) has not been fully elucidated. Objective: We aimed to examine the relationship between the systemic immune inflammation index (Sıı), which corresponds to the multiplying of the neutrophil-to-lymphocyte ratio (NLR) and the platelet counts, and isolated CE. Method: The retrospective study population included 200 patients with isolated CE, 200 consecutive with obstructive coronary artery disease, and 200 consecutive with a normal coronary artery angiogram. A 2-sided p-value of <0.05 was considered significant. Results: Sıı, NLR, platelet-to-lymphocyte ratio (PLR), and monocyte-to-high density lipoprotein cholesterol ratio (MHR) were significantly higher in the CE group compared with the other groups (all p<0.001). In multivariate analysis, Sıı (p<0.001, OR = 1.005, 95% CI =1.004-1.005) was found to be an independent predictor of isolated CE. In Receiver Operating Characteristic curve analysis, Sıı had a higher Area Under the Curve than NLR, PLR, and MHR. Sıı value of >517.35 has 79% sensitivity, 76% specificity for the prediction of the CE [AUC: 0.832, (p<0.001)]. Sıı had a significant correlation with the number of ectatic coronary arteries and Markis classification (r:0.214 p=0.002; r:-0.195, p=0.006, respectively). Conclusion: To the best of our knowledge, this is the first study that Sıı was significantly associated with isolated CE presence and anatomical severity. © 2023, Sociedade Brasileira de Cardiologia. All rights reserved.
dc.identifier.doi10.36660/abc.20220056
dc.identifier.issn0066-782X
dc.identifier.issue1
dc.identifier.pmid36629598
dc.identifier.scopus2-s2.0-85146193160
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.36660/abc.20220056
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26602
dc.identifier.volume120
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSociedade Brasileira de Cardiologia
dc.relation.ispartofArquivos Brasileiros de Cardiologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCoronary Artery Disease/complications; Dilatation Pathologic; Systemic Inflammation Immune
dc.titleSystemic Immune Inflammation Index is a Novel Marker in Predicting the Presence and Severity of Isolated Coronary Artery Ectasia
dc.title.alternativeO Índice de Inflamação Imune Sistêmica é um Novo Marcador na Previsão da Presença e Gravidade aa Ectasia Coronariana Isolada Artigo Original
dc.typeArticle

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