The short-term effects of various xenografts on bone healing in rats cranial defects

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dc.contributor.authorDevelioğlu, Hakan
dc.contributor.authorÖzcan, Gönen
dc.contributor.authorGültekin, Sibel Elif
dc.contributor.authorSengüven, Burcu
dc.contributor.authorYildirim, Ali
dc.date.accessioned2024-10-26T17:53:00Z
dc.date.available2024-10-26T17:53:00Z
dc.date.issued2018
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose: Xenografts can be used in dentistry and medicine for both clinical and experimental purposes. The goal of the investigation was to observe the short-term bone building outcomes of two xenografts (Gen Os and Gel 40) in the cranial bone defects in rats. Methods: Twelve rats were divided into two groups randomly, and a total of 24 parietal bone defects were created on the parietal bones. The symmetrical defects were in the critical size 5 mm and circular, which were treated with Gen Os in group 1, with Gel 40 in group 2, and symmetrical defects left empty as the controls. Rats were sacrificed 40 d after surgery, and the block sections, including the defects, were removed. The bone formation was assessed both histologically and histomorphometrically. Results: There was more bone building in the test groups when compared to the controls (p<0.05). Besides, no difference was seen between the two test groups (p>0.05). A significant difference was also found among the three groups regarding the inflammation scores (p<0.05). Conclusion: Within the limitations of the study, it can be concluded that both materials were osteoconductive, and more bone building was proved in the Gel 40 group. © 2018, Scientific Publishers of India. All rights reserved.
dc.identifier.doi10.4066/biomedicalresearch.29-17-3741
dc.identifier.endpage1602
dc.identifier.issn0970-938X
dc.identifier.issue8
dc.identifier.scopus2-s2.0-85047948796
dc.identifier.scopusqualityN/A
dc.identifier.startpage1598
dc.identifier.urihttps://doi.org/10.4066/biomedicalresearch.29-17-3741
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26659
dc.identifier.volume29
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherScientific Publishers of India
dc.relation.ispartofBiomedical Research (India)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBone building; Cranium defects; Xenografts
dc.titleThe short-term effects of various xenografts on bone healing in rats cranial defects
dc.typeArticle

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