Browsing by Author "Karahan, Oguz"
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Antiangiogenic activities of bemiparin sodium, enoxaparin sodium, nadroparin calcium and tinzaparin sodium
Dogan, Omer Tamer; Polat, Zubeyde Akin; Karahan, Oguz; Epozturk, Kursat; Altun, Ahmet; Akkurt, Ibrahim; Cetin, Ali (PERGAMON-ELSEVIER SCIENCE LTD, 2011)Introduction: The low-molecular-weight heparins have been demonstrated to have antiangiogenic effects in various assays. We aimed to demonstrate and compare the antiangiogenic effects of four types of commercially available ... -
The antiangiogenic effects of levosimendan in a CAM assay
Katrancioglu, Nurkay; Karahan, Oguz; Kilic, Ahmet Turhan; Altun, Ahmet; Katrancioglu, Ozgur; Polat, Zubeyde Akin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2012)Background: There is a physiological balance between the stimulatory and inhibitory signals for blood vessel growth. In many symptomatic patients with peripheral artery disease, coronary artery disease, and ischemic chronic ... -
Association of deep venous thrombosis with prothrombotic gene polymorphism identified in lung cancer cases
Arslan, Sulhattin; Manduz, Sinasi; Epozturk, Kursat; Karahan, Oguz; Akkurt, Ibrahim (SPRINGER, 2011)Venous thrombosis is a significant cause of morbidity and mortality in patients with malignancies. We aimed to investigate the association between prothrombotic gene polymorphisms detected in lung cancer cases and deep ... -
Associations between common 3435 C > T variants of the multi-drug resistance [MDR-1 (ABCB1)] gene and abdominal aortic aneurysm: a pilot study
Manduz, Sinasi; Katrancioglu, Nurkay; Karahan, Oguz; Yilmaz, Mehmet Birhan; Ozdemir, Ozturk; Berkan, Ocal (EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL, 2011)Background: The aim of the study was to reveal the effect of the C3435T MDR-1 gene polymorphism in AAA, which has been postulated to play a role in the inflammatory process and protection against oxidative stress. Methods: ... -
Chemokine receptor 5 Delta 32 gene polymorphism and abdominal aortic aneurysms
Aydin, Murat; Katrancioglu, Nurkay; Manduz, Sinasi; Atahan, Erhan; Karahan, Oguz; Ozdemir, Ozturk; Berkan, Ocai (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2010)Background: In this study, we aimed to investigate the relationship between abdominal aortic aneurysm (AAA) and chemokine receptor 5 Delta 32 (CCR5) gene polymorphism as a risk factor. Methods: Fifty-eight patients (41 ... -
Comparison of the antiangiogenic effects of heparin sodium, enoxaparin sodium, and tinzaparin sodium by using chorioallantoic membrane assay
Katrancioglu, Nurkay; Karahan, Oguz; Kilic, Ahmet Turhan; Altun, Ahmet; Katrancioglu, Ozgur; Polat, Zubeyde Akin (LIPPINCOTT WILLIAMS & WILKINS, 2012)Unfractionated heparin (UFH) and low molecular weight heparins have been used as anticoagulation agents in cardiovascular clinics for decades. However, these molecules also have potent antiangiogenic effects. Whereas, ... -
Determining the risk and frequecy of coronary artery disease in patients who have peripheric vascular occlusive disease and who will have vascular surgery
Tunel, H. Ali; Manduz, Sinasi; Katrancioglu, Nurkay; Karahan, Oguz; Berkan, Oecal (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2009)Background: The purpose of our study was to observe risks and frequency of coronary artery disease (CAD) in patients who had peripheral occlusive vascular disease (POVD) but who did not have symptoms of CAD, to determine ... -
Effect of Levosimendan in Patients with Severe Systolic Heart Failure and Worsening Renal Function
Zorlu, Ali; Yucel, Hasan; Yontar, Osman Can; Karahan, Oguz; Tandogan, Izzet; Katrancioglu, Nurkay; Yilmaz, Mehmet Birhan (ARQUIVOS BRASILEIROS CARDIOLOGIA, 2012)Background: Levosimendan, a calcium sensitizer, increases the sensitivity of the heart to calcium, thus increasing myocardial contractility without a rise in intracellular calcium. It was recently shown that levosimendan ... -
Familial genetic risk factors in premature cardiovascular disease: a family study
Yucel, Oguzhan; Karahan, Oguz; Zorlu, Ali; Manduz, Sinasi (SPRINGER, 2012)Cardiovascular disease (CVD) is closely associated with familial predisposition. The aim of the present study was to investigate predisposing risk factors in the family of a young patient who underwent coronary artery ... -
Frequency of the mdr-1 C > T gene polymorphism in patients with COPD
Dogan, Omer Tamer; Katrancioglu, Nurkay; Karahan, Oguz; Sanli, Gulizar Canan; Zorlu, Ali; Manduz, Sinasi (HOSPITAL CLINICAS, UNIV SAO PAULO, 2010)BACKGROUND AND AIM: The multi-drug resistant-1 (MDR-1) gene is located on human chromosome 7 and encodes a glycosylated membrane protein that is a member of the ATP-binding cassette transporters superfamily. The aim of the ... -
Influence of albumin concentration in priming solution on blood viscosity under hypothermic conditions
Sapmaz, Ismail; Manduz, Sinasi; Sanri, Umut S.; Karahan, Oguz; Dogan, Kasim (CLINICS CARDIVE PUBL PTY LTD, 2009)Objective: Albumin is used routinely as a plasma volume expander in cardiopulmonary bypass operations. The effect of two different concentrations of albumin in Ringer's lactate on blood viscosity was explored in this study. ... -
The influence of priming solutions used in cardiopulmonary bypass on blood viscosity in hypothermic conditions
Manduz, Sinasi; Sapmaz, Ismail; Sanri, Umut Serhat; Karahan, Oguz; Bascil, Hasan; Dogan, Kasim (LIPPINCOTT WILLIAMS & WILKINS, 2008)Vessel diameter, flow velocity, temperature, and viscosity are among the factors determining blood flow in vessels. To assess the influence of arterial blood flow on veins in a cardiac operation, the viscosity of blood ... -
The Investigation of the Antiangiogenic Potential of Amiodarone HCl in the Chick Embryo Chorioallantoic Membrane Model
Karahan, Oguz; Yavuz, Celal; Demirtas, Sinan; Caliskan, Ahmet; Atahan, Erhan (SCIENTIFIC PUBLISHERS INDIA, 2013)Angiogenesis, which plays a significant role in a variety of physiological processes, such as embryonic growth and wound healing, is strictly delimited and finely tuned by a balance of proangiogenic and antiangiogenic ... -
Is sustained release of vancomycin from fibrin glue effective to prevent methicillin-resistant Staphylococcus aureus graft infection?
Katrancioglu, Nurkay; Karahan, Oguz; Kilic, Ahmet Turhan; Katrancioglu, Ozgur; Celik, Cem; Bakici, Mustafa Zahir; Atahan, Erhan (ACADEMIC JOURNALS, 2012)Prosthetic vascular graft infection remains one of the most serious complications seen after vascular surgery. Recently, fibrin glue has gained attention as a possible means to deliver drug therapies. In this study, the ... -
PAI-1 4G/4G GENE POLYMORPHISM IS AFFECTING OF SERUM LIPID LEVEL IN TURKISH POPULATION
Katrancioglu, Nurkay; Manduz, Sinasi; Karahan, Oguz; Atahan, Erhan; Sanri, Umut Serhat; Berkan, Ocal (ELSEVIER IRELAND LTD, 2010)… -
Repair of Anomalous Origin of the Left Coronary Artery Arising from Right Pulmonary Artery with Rolled-Conduit-Extended Reimplantation in an Adult
Erdinc, Melih; Hosgor, Kemalettin; Karahan, Oguz (WILEY-BLACKWELL, 2011)The left coronary artery arising from the pulmonary artery (ALCAPA) is a rare congenital anomaly. It causes high mortality if untreated in childhood. Only 10% to 15% of patients reach adulthood. We report a successful ... -
Role of CA-125 in Identification of Right Ventricular Failure in Chronic Obstructive Pulmonary Disease
Yilmaz, Mehmet Birhan; Zorlu, Ali; Dogan, Omer Tamer; Karahan, Oguz; Tandogan, Izzet; Akkurt, Ibrahim (WILEY-BLACKWELL, 2011)Background: Chronic obstructive pulmonary disease (COPD) is a progressive and debilitating disease. Cor pulmonale, characterized by right ventricular (RV) failure, can severely influence prognosis in these patients. Hence, ...