Browsing by Author "Ozdemir, Ozturk"
Now showing items 41-50 of 50
-
The prevalence of VKORC1 1639 G > A and CYP2C9*2*3 genotypes in patients that requiring anticoagulant therapy in Turkish population
Silan, Coskun; Dogan, Omer Tamer; Silan, Fatma; Kukulguven, Fatma Mutlu; Asgun, Halil Fatih; Ozdemir, Semra; Uludag, Ahmet; Atik, Sinem; Gungor, Buket; Akdur, Secil; Aksulu, Hakki Engin; Ozdemir, Ozturk (SPRINGER, 2012)The aim was to investigate the prevalence of VKORC1 and CYP2C9 genotypes in patients requiring anticoagulant therapy in two different region's populations of Turkey. The recent cohort included 292 patients that needed ... -
Prevelance of Common YMDD Motif Mutations in Long Term Treated Chronic HBV Infections in a Turkish Population
Alagozlu, Hakan; Ozdemir, Ozturk; Koksal, Binnur; Yilmaz, Abdulkerim; Coskun, Mahmut (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)In the current study we aimed to show the common YMDD motif mutations in viral polymerase gene in chronic hepatitis B patients during lamivudine and adefovir therapy. Forty-one serum samples obtained from chronic hepatitis ... -
A Prospective Case-Control Study Analyzes 12 Thrombophilic Gene Mutations in Turkish Couples with Recurrent Pregnancy Loss
Yenicesu, Gonca Imir; Cetin, Meral; Ozdemir, Ozturk; Cetin, Ali; Ozen, Filiz; Yenicesu, Cem; Yildiz, Caglar; Kocak, Nadir (WILEY, 2010)Problem Recurrent pregnancy loss (RPL) is a heterogeneous disorder. The contribution of specific thrombophilic genes to the pathophysiology of RPL has remained controversial. We evaluated the prevalences of 12 thrombophilic ... -
The protective effect of MCP-1-2518 A > G promoter polymorphism in Turkish chronic renal failure patients requiring long-term hemodialysis
Bagci, Binnur; Bagci, Gokhan; Candan, Ferhan; Ozdemir, Ozturk; Sezgin, Ilhan (SPRINGER, 2015)Monocyte chemoattractant protein-1 (MCP-1) plays a major role in the pathogenesis and progression of different types of human renal disease. Therefore, in this study, we aimed to investigate the effect of MCP-1 gene -2518 ... -
The Proto-Oncogene KRAS and BRAF Profiles and Some Clinical Characteristics in Colorectal Cancer in the Turkish Population
Ozen, Filiz; Ozdemir, Semra; Zemheri, Ebru; Hacimuto, Gizem; Silan, Fatma; Ozdemir, Ozturk (MARY ANN LIEBERT INC, 2013)Objectives: The aim of the current study was to investigate the prevalence and predictive significance of the KRAS and BRAF mutations in Turkish patients with colorectal cancer (CRC). Methods: Totally, 53 fresh tumoral ... -
Recurrent Pregnancy Loss and Its Relation to Combined Parental Thrombophilic Gene Mutations
Ozdemir, Ozturk; Yenicesu, Gonca Imir; Silan, Fatma; Koksal, Binnur; Atik, Sinem; Ozen, Filiz; Gol, Mert; Cetin, Ali (MARY ANN LIEBERT, INC, 2012)Background and Aim: Recurrent pregnancy loss (RPL) is a heterogeneous disorder that has been associated with antiphospholipid syndrome and other prothrombotic parameters. We aimed to investigate the prevalence of 12 ... -
The role of apoptosis and protective effect of carnitine in contralateral testicular injury in experimental unilateral testicular torsion
Cankorkmaz, Levent; Koyluoglu, Gokhan; Ozer, Hatice; Yildiz, Esin; Sumer, Zeynep; Ozdemir, Ozturk (TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2009)BACKGROUND We examined the role of programmed cell death (PCD) in the etiology of contralateral testis injury as well as the protective effect of carnitine. METHODS Thirty-six Wistar Albino rats were used in the study. ... -
SRY and AZF gene variation in male infertility: a cytogenetic and molecular approach
Ozdemir, Ozturk; Gul, Eylem; Kilicarslan, Hakan; Gokce, Goekhan; Beyaztas, Fatma Y.; Ayan, Semih; Sezgi, Ihan (SPRINGER, 2007)Aim The aim of this study was to identify the genetic effects of Y chromosome and azoospermia factor (AZF) gene variation in men with infertility and to elucidate the molecular mechanism responsible for the identified point ... -
The thrombophilic gene polymorphisms and recurrent pregnancy loss dilemma: From Minsk/Belarus and Canakkale - Sivas/Turkish populations
Silan, Fatma; Mosse, Irma; Gonchar, Alexander; Sedlyar, Nikita; Kilchevsky, Alexander V.; Kuru, Banu; Ozdemir, Ozturk; Ozdemir, Ozturk (ELSEVIER SCIENCE BV, 2016)… -
Tissue specific epigenetic silencing of the distinct tumor suppressor genes in lung cancer
Arslan, Sulhattin; Karadayi, Sule; Ozdemir, Ozturk; Sahin, Ekber; Ozdemir, Semra; Akkurt, Ibrahim (ACADEMIC JOURNALS, 2010)The role of aberrant methylation of the cytosine-guanine dinucleotide islands in the promoter region of tumor suppressor genes in lung cancer development is increasingly recognized. DNAs extracted from cancer tissue biopsies ...