Adult height in Turkish patients with Turner syndrome without growth hormone treatment
dc.contributor.author | Bereket, Abdullah | |
dc.contributor.author | Turan, Serap | |
dc.contributor.author | Elcioglu, Nursel | |
dc.contributor.author | Hacihanefioglu, Seniha | |
dc.contributor.author | Memioglu, Nihal | |
dc.contributor.author | Bas, Firdevs | |
dc.contributor.author | Bundak, Rueveyde | |
dc.contributor.author | Darendeliler, Feyza | |
dc.contributor.author | Guenoez, Huelya | |
dc.contributor.author | Saka, Nurcin | |
dc.contributor.author | Ercan, Oya | |
dc.contributor.author | Arslanoglu, Ilknur | |
dc.contributor.author | Isgueven, Pinar | |
dc.contributor.author | Yildiz, Metin | |
dc.contributor.author | Can, Sule | |
dc.contributor.author | Oezerkan, Ebru | |
dc.contributor.author | Coker, Mahmut | |
dc.contributor.author | Darcan, Suekran | |
dc.contributor.author | Oezkan, Behzat | |
dc.contributor.author | Orbak, Zerrin | |
dc.contributor.author | Oeztas, Sitki | |
dc.contributor.author | Palanduez, Suekrue | |
dc.contributor.author | Sezgin, Ilhan | |
dc.contributor.author | Atabek, Emre | |
dc.contributor.author | Erkul, Ibrahim | |
dc.contributor.author | Erdogan, Guerbuez | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:15:03Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:15:03Z | |
dc.date.issued | 2008 | |
dc.identifier.issn | 0041-4301 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/10327 | |
dc.description | WOS: 000261531400001 | en_US |
dc.description | PubMed ID: 19102043 | en_US |
dc.description.abstract | Spontaneous adult height (AH) in Turner syndrome (TS) varies among populations. Population-specific AH data is essential to assess the efficacy of growth-promoting therapies in TS. A multicenter study was performed to establish AH of non-growth hormone (GH)-treated Turkish patients with TS. One hundred ten patients with TS (diagnosed by karyotype) who reached AH (no growth in the previous year, or bone age > 15 years) without receiving GH treatment were included in the study. The average AH was found to be 141.6 +/- 7.0 cm at the age of 22.9 +/- 6.2 years, which is 18.4 cm below the population average and 16.4 cm below the patients' mid-parental heights. Bone age at start of estrogen replacement was 12.3 +/- 1.3 year. Karyotype distribution of the patients was 45X (43%), 4SX/46XX (16%), 4SX/46xi (12%), 45XiXq (10%) and others (19%). When the patients were evaluated according to their karyotype as 45X and non-45X, no significant difference in AH was observed (142.4 +/- 6.9 cm vs 140.9 +/- 7.1 cm, respectively). Adult height of non-GH-treated Turkish TS patients obtained in this study was comparable to that of other Mediterranean populations, but shorter than that of Northern European patients. Karyotype does not seem to affect AH in TS. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | TURKISH J PEDIATRICS | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Turner syndrome | en_US |
dc.subject | final height | en_US |
dc.subject | adult height | en_US |
dc.subject | karyotype | en_US |
dc.subject | growth | en_US |
dc.subject | growth hormone | en_US |
dc.title | Adult height in Turkish patients with Turner syndrome without growth hormone treatment | en_US |
dc.type | article | en_US |
dc.relation.journal | TURKISH JOURNAL OF PEDIATRICS | en_US |
dc.contributor.department | [Bereket, Abdullah -- Turan, Serap -- Elcioglu, Nursel] Marmara Univ, Fac Med, Dept Pediat, Istanbul, Turkey -- [Hacihanefioglu, Seniha] Istanbul Univ, Dept Genet, Cerrahpasa Fac Med, Istanbul, Turkey -- [Ercan, Oya] Istanbul Univ, Dept Pediat, Cerrahpasa Fac Med, Istanbul, Turkey -- [Bas, Firdevs -- Bundak, Rueveyde -- Darendeliler, Feyza -- Guenoez, Huelya -- Saka, Nurcin -- Palanduez, Suekrue] Istanbul Univ, Dept Pediat, Istanbul Fac Med, Istanbul, Turkey -- [Memioglu, Nihal] Sisli Etfal State Hosp, Dept Pediat, Div Pediat Endocrinol, Istanbul, Turkey -- [Arslanoglu, Ilknur -- Isgueven, Pinar -- Yildiz, Metin] Goztepe State Hosp, Istanbul, Turkey -- [Can, Sule -- Oezerkan, Ebru] Tepecik State Hosp, Izmir, Turkey -- [Coker, Mahmut -- Darcan, Suekran] Ege Univ, Fac Med, Dept Pediat, Izmir, Turkey -- [Oezkan, Behzat -- Orbak, Zerrin -- Oeztas, Sitki] Ataturk Univ, Fac Med, Dept Pediat, Erzurum, Turkey -- [Sezgin, Ilhan] Cumhuriyet Univ, Fac Med, Dept Med Genet, Sivas, Turkey -- [Atabek, Emre -- Erkul, Ibrahim] Selcuk Univ, Fac Med, Dept Pediat, Konya, Turkey -- [Erdogan, Guerbuez] Ankara Univ, Fac Med, Dept Endocrinol, TR-06100 Ankara, Turkey | en_US |
dc.contributor.authorID | Turan, Serap -- 0000-0002-5172-5402 | en_US |
dc.identifier.volume | 50 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.endpage | 417 | en_US |
dc.identifier.startpage | 415 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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