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Investigation Cytotoxic effect of HSP70 Inhibitör JG-98 0n K562 Chronic Myeloid Leukemia Cells
(2022/09/18)
Abstract
Hsp70 weighs approximately 70 kDa (66-78 kDa) and is the best-preserved and best characterized Hsp family among living organisms [1]. Hsp70 is a molecular chaperone with
physiological roles such as folding of ...
Pregnancy and Cytokines, Cytokines and Diseases
(2022)
ABSTRACT
Pregnancy is a physiological state designated as the regional immune tolerance of the mother organism against paternal sourced antigens found in embryonic cells. While the paternal heritage makes half of the ...
Predictive and Prognostic Value of Plasma Zonulin for Gestational Diabetes Mellitus in Women at 24–28 Weeks of Gestation
(2022/12)
Objective We aimed to examine the predictive and prognostic value of plasma zonulin for gestational diabetes mellitus (GDM) in women at 24–28 weeks of gestation.
Methods This retrospective study was carried out with ...
The effect of embryo transfer technique on pregnancy and live birth rates in infertile women undergoing IVF treatment with freeze-all strategy
(2022)
Abstract
Objective: The aim of this observational retrospective cohort study was to define the effect of the embryo transfer (ET) technique on pregnancy and live birth rates. Material and Methods: Infertile women with ...
Prediction of gestational diabetes mellitus and perinatal outcomes by plasma zonulin levels
(2022/8/22)
Abstract
Purpose: Zonulin has been shown to be associated with many metabolic disorders, including type 2 diabetes mellitus, metabolic syndrome, and obesity. In this study, we aimed to evaluate the association between ...
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
(2023/2)
Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension (GHT).
Methods ...
Anticancer activity of Heat Shock Protein 70 (HSP70) Inhibitor, JG-98, against human cervical cancer HeLa and ovarian cancer SKOV-3 cells
(Medicine Science International Medical Journal, 2023/3/1)
Abstract
Cervical and ovarian cancer are two aggressive neoplasms for women, still with high mortality and morbidity. Among the molecules and compounds that have
anticancer activity, it was studied the JG-98, a heat shock ...
Collaborative Clinical Research on Metabolomics
(23.10.2023)
Metabolomics is the scientific study of chemical processes involving metabolites, substrates, intermediates, and namely all reagents and products of cell metabolism. Metabolomics and Clinical Approach will contribute to ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
(Galenos Yayinevi Tic. Ltd., Eylül/2023)
Objective
This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model.
Materials and Methods
Five groups were formed with eight ...
The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum
(2023/9/30)
ABSTRACT
History
Received: 11/04/2023
Accepted: 22/09/2023
Hyperemesis gravidarum (HG) has severe, dramatic consequences, and the cause of this severe disease has not
yet been determined clearly. It is known that ...