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Chemical and functional composition and biological activities of Anatolian Hypericum scabrum L. plant
(2023)
Hypericum scabrum L. plant has wide use in ethnopharmacology and is cultivated both naturally and technologically. This study was conducted to determine chemical and functional properties and in vitro biological activities ...
Synthesis of novel Cu(II) complexes with N2O2 ligands: Characterization, theoretical calculations, antimicrobial, antioxidant, DNA binding, and in vitro anticancer activity studies
(2023)
The aim was to investigate the in vitro antimicrobial, antioxidant, cytotoxic activities and pBR322 Plasmid DNA interaction potentials of newly synthesized Schiff bases and their copper complexes. Cytotoxic activities of ...
Investigation of gene expression levels in thyroid tissues of rats treated with Wi-Fi electromagnetic wave (2.4–3 GHz Wi-Fi RF-EMF)
(2023)
A B S T R A C T
In this study, it was aimed to examine the effects of wireless waves applied to rats in the thyroid tissue by
evaluating gene expression levels on 12 determined gene regions. 20 healthy 16-week-old Wistar ...
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(MDPI, 01.12.2023)
Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body.
Objectives: In this study, we aimed to investigate the relationship between ...
Composition characterization and biological activity study of Achillea vermicularis extract and extract‐loaded nanoparticles
(JUMB, 2023/1/9)
Antiproliferative activity of Achillea vermicularis extracts was calculated on glial (C6) and keratinocyte (HaCaT) cell lines using XTT assay. It was observed that all extracts of A. vermicularis at the determined concentration ...
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 2023/9/15)
Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The
resin obtained from this plant is effective for different diseases. The chemical content of the ethanol ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death
(2023)
Objective: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse
model.
Materials and Methods: Five groups were formed with eight ...
Leukotriene metabolism and proiflammatory cytokines in Crimean Congo hemorrhagic fever
(01.01.2023)
Crimean–Congo hemorrhagic fever (CCHF) is an emerging acute viral infection disease, yet its pathophysiology remains largely uncharacterized. Lipid mediators are molecules that play numerous roles in the physiologic and ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com- pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ...
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
(WİLEY, 2023/11)
The cytotoxic activities of the compounds were determined by the 3‐(4,
5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human
breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ...