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Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
(Elsevier, 2022/09/15)
Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity,
butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone ...
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
(Elsevier, 2022/12/05)
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds ...
Synthesis and biological evaluation of thiosemicarbazone derivatives
(Springer US, 2022/07/21)
In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were ...
Biological effects and molecular docking studies of Catechin 5-O-gallate: Antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Taylor & Francis, 2022/04/13)
Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ...