Fakülteler: Recent submissions
Now showing items 1821-1840 of 2389
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Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
(Elsevier, 2021/15/09)DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ... -
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
(Springer, 2021/05/04)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
(Elsevier, 2021/11/1)Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ... -
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
(2021/6)In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ... -
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
(2021/9/15)DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ... -
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
(Elsevier, 1 November)Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ... -
IL‑13 Gene Polymorphisms (‑1112 C/T and ‑1512 A/C) in Patients with Chronic and Aggressive Periodontitis: Effects on GCF and Outcome of Periodontal Therapy
(Medical and Dental Consultants’ Association of Nigeria, 2021)Background: IL‑13 is the key cytokine in the regulation of inflammatory with an autoimmune disease and has an anti‑inflammatory effect. Aims: This study aimed to compare IL‑13 (‑1112 C/T and ‑1512 A/C) gene polymorphisms in ... -
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ... -
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ... -
Synthesis of PEGylated nanographene oxide as a nanocarrier for docetaxel drugs and anticancer activity on prostate cancer cell lines
(SAGE Publishing, 2021)Graphene oxide (GO) has recently been considered one of the most promising carbon derivatives in nanotechnology. It has many excellent features such as tumor targeting ability, biocompatibility and low toxicity. Therefore, ... -
Increased frequency of occurrence of bendopnea is associated with poor outcomes in heart failure outpatients
(Taylor&Francis, Ekim 2021)Background: Relationship between the frequency of occurrence of bendopnea during the daily life of heart failure (HF) outpatients and clinical outcomes has never been evaluated before. Methods: Turkish Research Team-Heart ... -
Serum Melatonin as a Biomarker for Assessment of Late-term and Postterm Pregnancies in Women without Spontaneous Onset of Labor
(Georg Thieme Verlag KG, 2021/12)We conducted a prospective study to assess serum melatonin as a biomarker to predict the development of late-term and postterm pregnancies and spontaneous beginning of labor in women with term pregnancies. Population of ... -
The Healing Effects of The Topical Mesenchymal Stem Cells Application on Colonic Anastomosis Subjected to Ischemia Reperfusion Injury
(2021)Intestinal ischemia reperfusion injury (IRI) is a challenging problem and it adversely affects the healing of colonic anastomosis. Our experimental study aimed to investigate the role of mesenchymal stem cells (MSC) ... -
The evaluation of intracellular energy metabolism in prediabetic patients and patients newly diagnosed with type 2 diabetes mellitus
(2021)Background/aim: Increased susceptibility to infections is a serious problem in diabetics. Impairment in the energy metabolism of the immune system is the main source of the problem. Early diagnosis of the impairment in ... -
Does the laminar iirflow system affect the development of perioperative hypothermia? a randomized clinical trial
(2021)Objectives: We aimed to compare tympanic membrane temperature changes and the incidence of inadvertent perioperative hypothermia (IPH) in patients undergoing laparoscopic cholecystectomy under general anesthesia in laminar ... -
Cancer antigen-125 is a predictor of mortality in patients with pulmonary arterial hypertension
(Elsevier, Mart 2021)Abstract Background: Carbohydrate antigen 125 (CA 125), known as a tumor marker for ovarian cancer, has been reported to increase and be associated with severity in heart failure and chronic obstructive pulmonary disease. ... -
Epigenetics and Autoimmunity
(Cambridge Scholar publication, 2021)The immune system is a complex system that forms the defense mechanism against diseases in a living thing, recognizes and destroys pathogens and tumor cells, and protects the body from foreign and harmful substances. ... -
Autoimmunity and genetics
(Cambridge Scholar publication, 2021)Unlike 50 years ago, autoimmunity is today a widely recognized phenomenon with registered cases encompassing more than 5% of the world populace with at least 40 different autoimmune disorders (Mori et al. 2005). Notwithstanding ... -
Fabric-Phase Sorptive Membrane Array As a Noninvasive In Vivo Sampling Device For Human Exposure To Different Compounds
(ACs, 20.01.2021)This study introduces an innovative device for the noninvasive sampling and chromatographic analysis of different compounds present in exhaled breath aerosol (EBA). The new sampling device, especially in light of the ... -
Sensitive determination of Fluoxetine and Citalopram antidepressants in urine and wastewater samples by liquid chromatography coupled with photodiode array detector
(Elsevier, 26.04.2021)A new analyte separation and preconcentration method for the trace determination of antidepressant drugs, Fluoxetine (FLU) and Citalopram (CIT) in urine and wastewaters, was developed based on HPLC- DAD analysis after ...