Search
Now showing items 1-5 of 5
Pyrazolyl‐Benzoxazinone Derivatives as Dual Hsp Inhibitors in Human Breast Cancer
(2022)
Heat Shock Proteins (Hsps) play major role on the onset of several cancers. Metabolic rates of cancer cells are higher compared to that of untransformed cells. This accelerated rate force functional substrate proteins to ...
Possible effects of clinoptilolite on small intestinal ischemia-reperfusion injury caused by experimental mesenteric artery occlusion
(2022)
Objectives: Mesenteric ischemia is a surgical emergency caused by poor blood supply to the intestines. In ischemia,the decrease in blood flow to the tissue causes acidosis and cell death through anaerobic metabolism. ...
Design, synthesis and in vitro antiproliferation activity of some 2-aryl and -heteroaryl benzoxazole derivatives
(2022)
Background: Phortress produces reactive electrophilic metabolites that form DNA adducts only in
sensitive tumor cells. The authors converted the 2-phenylbenzothiazole nucleus in phortress to 2-
aryl and -heteroaryl ...
circRNAs in drug resistance of breast cancer
(2022)
Abstract: Breast cancer (BC) is the most common heterogeneous disease in women and one of the leading causes of cancer-related death. Surgery, chemotherapy, radiotherapy, hormone, and targeted therapy are the gold standards ...
Synthesis, Biological Evaluation and In Silico Studies of Some 2‐Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
(2022)
In an attempt to develop potent and selective anticancer agents, some 5- or 6- and N-substituted benzoxazol-2-carbox amide derivatives were designed, synthesized, and evaluated for their cyclooxygenase inhibitory, antioxidant, ...