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Pharmacokinetic Profiles of Metamizole Metabolites after Intramuscular and Intravenous Administration in Healthy Arabian Horses
(2021)
Metamizole sodium (MT) is an analgesic and antipyretic drug molecule used in humans,
horses, cattle, swine, and dogs. Metamizole rapidly hydrolyzes and turns into methyl amino antipyrine (MAA), an active primary metabolite ...
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
(2021/9/15)
DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ...
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
(Elsevier, 1 November)
Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ...