Search
Now showing items 31-40 of 40
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)
Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ...
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
(Galenos Yayinevi Tic. Ltd., Eylül/2023)
Objective
This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model.
Materials and Methods
Five groups were formed with eight ...
Experimental and theoretical insights about the effect of some newly designed azomethine group‐contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In
recent years, ...
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)
Background:
Fibromyalgia is a soft tissue rheumatism characterized by chronic and
widespread musculoskeletal pain at specific points in the body.
Objectives:
In this study, we aimed to investigate the relationship ...
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
(Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany, 2023/2)
Abstract
Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension ...
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 2023/9/15)
Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The
resin obtained from this plant is effective for different diseases. The chemical content of the ethanol ...
Leukotriene metabolism and proiflammatory cytokines in Crimean Congo hemorrhagic fever
(01.01.2023)
Crimean–Congo hemorrhagic fever (CCHF) is an emerging acute viral infection disease, yet its pathophysiology remains largely uncharacterized. Lipid mediators are molecules that play numerous roles in the physiologic and ...
The Effect of Methylphenidate Treatment on Olfactory Function in Children and Adolescents With ADHD
(Journal of Attention Disorders, 06.05.2023)
Objective: This study aimed to research whether there is an olfactory disorder in ADHD, and if so, what is the effect of methylphenidate on this condition. Method: This is a cross-sectional study aiming to evaluate olfactory ...
Evaluation of cognitive disengagement syndrome in children with obsessive-compulsive disorder: Clinical implications
(Clinical Child Psychology and Psychiatry, 18.04.2023)
Cognitive disengagement syndrome (CDS) has been found to be associated with internalizing symptoms. Yet, no study thus far has focused on whether there is an association between obsessive- compulsive disorder (OCD) and ...