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Relationship between Systemic Immune-inflammation Index and Mortality in Intensive Care Patients Diagnosed with Crimean-Congo Hemorrhagic Fever
(Journal of the College of Physicians and Surgeons Pakistan, 2022)
Objective: To evaluate the power of the systemic immune-inflammation index in the prediction of mortality in severe Crimean--Congo hemorrhagic fever patients.
Study Design: Observational study.
Place and Duration of ...
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats
(Elsevier, 2022)
The toxicity of acetaminophen (N-acetyl-para-aminophenol (APAP)) is the most frequent cause of drug-induced liver damage. Galium aparine L. (GA) is traditionally used to treat jaundice. We aimed to investigate the ...
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)
Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ...
Investigation Cytotoxic effect of HSP70 Inhibitör JG-98 0n K562 Chronic Myeloid Leukemia Cells
(2022/09/18)
Abstract
Hsp70 weighs approximately 70 kDa (66-78 kDa) and is the best-preserved and best characterized Hsp family among living organisms [1]. Hsp70 is a molecular chaperone with
physiological roles such as folding of ...
Synthesis, computational analyses, antibacterial and antibiofilm properties of nicotinamide derivatives
(Ağustos 20)
Newly designed nicotinamide derivatives were synthesized and characterized using spectral techniques (IR, 1H-NMR, 13C-NMR, and MS). Moreover, these compounds are investigated computationally. B3LYP/6–31 + G(d,p) level is ...
The 5-HT7 receptor antagonist SB-269970 alleviates seizure activity and downregulates hippocampal c-Fos expression in pentylenetetrazole-induced kindled rats
(NEUROLOGICAL RESEARCH, 2022)
Objectives: Recently, studies have demonstrated that serotonin type 7 receptors (5-HT7) have conflincting effects on neuronal excitability in different brain regions. However, the effect of 5-HT7 on seizures has not been ...
Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells
(Metabolic Brain Disease, 2022)
Recent studies have shown that angiotensin-converting enzyme (ACE) inhibitors have reduced oxidative damage in the central nervous system (CNS). Accumulating evidence have also demonstrated that captopril, an ACE inhibitor, ...
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
(2023/2)
Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension (GHT).
Methods ...
Determination of Ongoing Symptoms, Quality of Life Levels, and Risk Factors in Post-COVID-19 Patients
(MART 2022)
Objective: Studies have reported that most post-COVID-19 patients experience post-disease symptoms, but the results of
these studies have not been interpreted correctly. The present study aimed to determine the ongoing ...
4th INTERNATIONAL CANCER DAYS CONGRESS BOOK
(Sivas Cumhuriyet Üniversitesi, 2023)
Sivas Cumhuriyet Üniversitesi