dc.contributor.author | Altunay, Nail | |
dc.date.accessioned | 2022-05-11T06:28:16Z | |
dc.date.available | 2022-05-11T06:28:16Z | |
dc.date.issued | 2021 | tr |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/12765 | |
dc.description.abstract | This study report optimization of vortex-assisted natural deep eutectic solvent based liquid-phase microextraction (VA-NADES-LPME) for determination of indigo-carmine in some food samples by UV–Visible spectrophotometer. To ensure efficient extraction, nine different NADES were prepared and tested for the extraction of indigo-carmine. In order to increase extraction efficiency of indigo-carmine, the effects of VA-NADES-LPME variables and their interactions were optimized with central composite design. The optimized method exhibited a linear range between 10 and 900 ng mL−1. Limit of detection, limit of quantification and enrichment factor were determined as 3.3 ng mL−1, 10 ng mL−1 and 135-fold, respectively. The applicability of the optimized method was investigated in selected food samples using the matrix-matching calibration curve. Using optimised experimental conditions (pH of 3.2, 75 µL of NADES-4, 285 µL of THF, and 4 min vortexing), satisfactory recovery results were found in the range of 95.9–104.2% with 1.4–3.7% of relative standard deviation. Finally, the optimized method was economical, simple, green, requires less laborious sampling, and provides superior accuracy and precision in trace-level analysis. | tr |
dc.language.iso | eng | tr |
dc.publisher | Elsevier | tr |
dc.relation.isversionof | 10.1016/j.saa.2021.119791 | tr |
dc.rights | info:eu-repo/semantics/closedAccess | tr |
dc.subject | Indigo-carmineExperimental modellingSpectrophotometryNatural deep eutectic solventsFood samplesCentral composite design | tr |
dc.title | An optimization approach for fast, simple and accurate determination of indigo-carmine in food samples | tr |
dc.type | article | tr |
dc.relation.journal | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | tr |
dc.contributor.department | Fen Fakültesi | tr |
dc.identifier.volume | 257 | tr |
dc.identifier.issue | 257 | tr |
dc.identifier.endpage | 119791 | tr |
dc.identifier.startpage | 119791 | tr |
dc.relation.publicationcategory | Uluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanı | tr |