Browsing Sivas Cumhuriyet Üniversitesi Veteriner Fakültesi by Subject "sacubitril, valsartan, doxorubicin, cardiotoxicity, heart failure"

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Angiotensin receptor-neprilysin inhibition by sacubitril/valsartan attenuates doxorubicin induced cardiotoxicity in a pretreatment mice model by interfering with oxidative stress, inflammation, and Caspase 3 apoptotic pathway

Dindaş, Ferhat; Güngör, Hüseyin; Ekici, Mehmet; Akokay, Pınar; Bayçumendur, Füsun Erhan; Doğduş, Mustafa; Yılmaz, Mehmet Birhan (AVES, 2021)

Objective: Doxorubicin (DOX) is a well-known cardiotoxic agent, whereas sacubitril/valsartan (Sac/Val) is an effective treatment option in heart failure. In this study, we aimed to evaluate the effect of Sac/Val on ...