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Architectural View of Flexible Aliphatic –OH Group Coordinated Hemi‑Directed Pb(II)‑Salen Coordination Polymer: Synthesis, Crystal Structure, Spectroscopic Insights, Supramolecular Topographies, and DFT Perspective
(27.01.2022, 27.01.2022)
We serendipitously designed one novel 1D hetero-binuclear Zn(II)-Pb(II) coordination polymer, namely [(Zn)(Pb)(L)(η1–
NCS)(η1–SCN)]n (1) from Salen ligand (
H3L) in the presence of NaSCN. The complex was structurally ...
1,2,3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
(09.12.2020)
In recent years, acetylcholinesterase (AChE) and a-glycosidase (a-gly) inhibition have emerged as a
promising and important approach for pharmacological intervention in many diseases such as glaucoma,
epilepsy, obesity, ...
Anti-quorum sensing activity in Pseudomonas aeruginosa PA01 of benzimidazolium salts: electronic, spectral and structural investigations as theoretical approach
(taylor francis, 01.03.2021)
Quorum sensing (QS) is a system used in the expression of virulence factors by many pathogenic bacteria,
and blockage of the system is seen as a new and effective strategy in combating with resistant bacteria.
The ...
Quinoline-fused both non-peripheral and peripheral ZnII and MgII phthalocyanines: Anti-cholinesterase, anti- α-glucosidase, DNA nuclease, antioxidant activities, and in silico studies
(08.04.2022)
Quinoline-fused ZnII (ZnPcp/ZnPcnp) and MgII (MgPcp/MgPcnp) phthalocyanines
with four 4-methylquinolin-2-ol (1) at non-peripheral or peripheral
positions of the phthalocyanine core have been synthesized via
cyclotetramerization ...
Unravelling the Synthetic Mimic, Spectroscopic Insights, and Supramolecular Crystal Engineering of an Innovative Heteronuclear Pb(II)‑Salen Cocrystal: An Integrated DFT, QTAIM/NCI Plot, NLO, Molecular Docking/PLIP, and Antibacterial Appraisal
(springer, 26.07.2022)
Spontaneous self-assembly in the supramolecular entity is one of the enthralling synthetic routes. It produces disparate structure crystal complexes after selecting suitable M-L combinations in the pseudohalide sense. In ...
Biological effects and molecular docking studies of Catechin 5-O-gallate: antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Journal of Biomolecular Structure and Dynamics, 04.10.2020)
Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer
of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically
active ...
Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3- mercapto-1,2,4-triazole
(PLOS ONE, 15.12.2022)
Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been synthesized
and evaluated against human liver cancer cell line (Hep G2) using MTT assay. The
synthesized series of azomethines exhibited ...
Experimental and theoretical investigation of corrosion inhibition effect of two piperazine-based ligands on carbon steel in acidic media
(4.02.2022)
hydroxyethyliminomethyl)
phenyl)piperazine (1) or its reduced form, 1,4-bis(2-(2-hydroxyethylaminomethyl)phenyl)piperazine
(2), as possible corrosion inhibitors, were compared to a solution containing no (1) or (2). The ...
Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and a-glycosidase enzymes inhibitors
(26.08.2020)
In the article, various substituted derivatives of 1,2-aminopropanthiol (1a–g) have been prepared by a general
and efficientmethod, in one-steps, starting fromavailable thiirane and aromatic amines (aniline, o-toluidine) ...
Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and α-glycosidase enzymes inhibitors
(27.08.2020)
In the article, various substituted derivatives of 1,2-aminopropanthiol (1a–g) have been prepared by a general
and efficientmethod, in one-steps, starting fromavailable thiirane and aromatic amines (aniline, o-toluidine) ...