dc.contributor.author | Nail ALTUNAY | |
dc.date.accessioned | 2023-04-11T10:39:41Z | |
dc.date.available | 2023-04-11T10:39:41Z | |
dc.date.issued | 2022 | tr |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/13496 | |
dc.description.abstract | In this research, a green, selective and inexpensive switchable hydrophilicity solvent-based liquid phase
microextraction (SHS-LPME) procedure has been optimized for the extraction and preconcentration of sulfadiazine (SDZ) in milk, honey and water samples prior to spectrophotometric analysis. Five variables affecting the SHS-LPME procedure were optimized using chemometric-based central composite design. For the SHS-LPME procedure, analytical parameters such as linearity, limit of detection, extraction recovery and enrichment factor were 15–300 μg L 1, 4.5 μg L 1, 96 ± 3% and 113, respectively. The precision of the method was investigated by repeatability and reproducibility studies. The relative standard deviation from these studies was found in the range of 2.4–4.5%. The recovery of the SDZ in the samples was in the range of 94 ± 4–99 ± 2%. Collected samples were analyzed by both the SHS-LPME procedure and the reference method using flow injection-flame atomic absorption technique, and the results were compared. There was no statistically significant difference between the two methods. This showed that the SHS-LPME procedure can be safely applied to the analysis of real samples. | tr |
dc.rights | info:eu-repo/semantics/closedAccess | tr |
dc.title | Chemometric design-based optimization of a green, selective and inexpensive switchable hydrophilicity solvent-based liquid phase microextraction procedure for pre-concentration and extraction of sulfadiazine in milk, honey and water samples | tr |
dc.type | article | tr |
dc.relation.journal | Food Chemistry | tr |
dc.contributor.department | Fen Fakültesi | tr |
dc.relation.publicationcategory | Uluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanı | tr |