dc.contributor.author | Yalazan, Halise | |
dc.contributor.author | Tüzün,Burak | |
dc.contributor.author | Akkaya, Didem | |
dc.contributor.author | Barut, Burak | |
dc.contributor.author | Kantekin, Halit | |
dc.contributor.author | Yıldırmıs, Sermet | |
dc.date.accessioned | 2023-04-12T05:31:45Z | |
dc.date.available | 2023-04-12T05:31:45Z | |
dc.date.issued | 08.04.2022 | tr |
dc.identifier.citation | Halise Yalazan1 | Burak Tüzün2 | Didem Akkaya3 | Burak Barut3 |
Halit Kantekin1 | Sermet Yıldırmıs¸3
1Faculty of Sciences, Department of
Chemistry, Karadeniz Technical
University, Trabzon, Turkey
2Plant and Animal Production
Department, Technical Sciences
Vocational School of Sivas, Sivas
Cumhuriyet University, Sivas, Turkey
3Faculty of Pharmacy, Department of
Biochemistry, Karadeniz Technical
University, Trabzon, Turkey | tr |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/13575 | |
dc.description.abstract | Quinoline-fused ZnII (ZnPcp/ZnPcnp) and MgII (MgPcp/MgPcnp) phthalocyanines
with four 4-methylquinolin-2-ol (1) at non-peripheral or peripheral
positions of the phthalocyanine core have been synthesized via
cyclotetramerization of phthalonitrile derivatives (CNp/CNnp) in the presence
of zinc (II) and magnesium (II) metal ions in this study. After synthesis and
characterization processes, anti-cholinesterase, anti-α-glucosidase, DNA
nuclease, antioxidant activities, and in silico calculations of both peripheral
and non-peripheral ZnII and MgII phthalocyanines were investigated. The
inhibitory effects of metallated phthalocyanines on acetylcholinesterase, butyrylcholinesterase,
and α-glucosidase enzymes were tested by spectrophotometric
method. Theoretical methods are used to compare both the chemical
and biological activities of the studied phthalonitrile derivatives and metallated
phthalocyanine compounds. | tr |
dc.language.iso | eng | tr |
dc.relation.isversionof | 10.1002/aoc.6696 | tr |
dc.rights | info:eu-repo/semantics/openAccess | tr |
dc.subject | anti-cholinesterase | tr |
dc.subject | anti-α-glucosidase | tr |
dc.subject | molecular docking | tr |
dc.subject | phthalocyanine | tr |
dc.subject | PLIP | tr |
dc.title | Quinoline-fused both non-peripheral and peripheral ZnII and MgII phthalocyanines: Anti-cholinesterase, anti- α-glucosidase, DNA nuclease, antioxidant activities, and in silico studies | tr |
dc.type | article | tr |
dc.relation.journal | Appl Organomet Chem. | tr |
dc.contributor.department | Sivas Meslek Yüksekokulu | tr |
dc.contributor.authorID | https://orcid.org/0000-0002-0420-2043 | tr |
dc.identifier.volume | 2022 | tr |
dc.identifier.startpage | e6696 | tr |
dc.relation.publicationcategory | Rapor | tr |