Clinical Characteristics and Outcome of COVID-19 in Turkish Hematological Malignancy Patients
dc.contributor.author | CİVRİZ BOZDAĞ SİNEM | |
dc.contributor.author | CENGİZ SEVAL GÜLDANE | |
dc.contributor.author | YÖNAL HİNDİLERDEN İPEK | |
dc.contributor.author | HİNDİLERDEN FEHMİ | |
dc.contributor.author | ANDIÇ NESLİHAN | |
dc.contributor.author | BAYDAR MUSTAFA | |
dc.contributor.author | AYDIN KAYNAR LALE | |
dc.contributor.author | TOPRAK SELAMİ KOÇAK | |
dc.contributor.author | GÖKSOY HASAN SAMİ | |
dc.contributor.author | BALIK AYDIN BERRİN | |
dc.contributor.author | DEMİRCİ UFUK | |
dc.contributor.author | CAN FERDA | |
dc.contributor.author | ÖZKOCAMAN VİLDAN | |
dc.contributor.author | GÜNDÜZ EREN | |
dc.contributor.author | GÜVEN ZEYNEP TUĞBA | |
dc.contributor.author | ÖZKURT ZÜBEYDE NUR | |
dc.contributor.author | DEMİRCİOĞLU SİNAN | |
dc.contributor.author | BEKSAÇ MERAL | |
dc.contributor.author | İNCE İDRİS | |
dc.contributor.author | YILMAZ UMUT | |
dc.contributor.author | EROĞLU KÜÇÜKDİLER AYŞE HİLAL | |
dc.contributor.author | ABİSHOV ELGÜN, | |
dc.contributor.author | YAVUZ BORAN | |
dc.contributor.author | ATAŞ ÜNAL | |
dc.contributor.author | MUTLU YAŞA GÜL | |
dc.contributor.author | BAŞ VOLKAN | |
dc.contributor.author | ÖZKALEMKAŞ FAHİR | |
dc.contributor.author | ÜSKÜDAR TEKE HAVA | |
dc.contributor.author | GÜRSOY VİLDAN | |
dc.contributor.author | ÇELİK SERHAT | |
dc.contributor.author | ÇİFTÇİLER RAFİYE | |
dc.contributor.author | YAĞCI ABDULLAH MÜNCİ | |
dc.contributor.author | TOPÇUOĞLU PERVİN | |
dc.contributor.author | ÇENELİ ÖZCAN | |
dc.contributor.author | ABBASOV HAMZA | |
dc.contributor.author | SELİM CEM | |
dc.contributor.author | AR MUHLİS CEM | |
dc.contributor.author | YÜCEL ORHAN KEMAL | |
dc.contributor.author | SADRİ SEVİL | |
dc.contributor.author | ALBAYRAK YAŞAR CANAN | |
dc.contributor.author | DEMİR AHMET MUZAFFER | |
dc.contributor.author | GÜLER NİL | |
dc.contributor.author | KEKLİK MUZAFFER | |
dc.contributor.author | TERZİ HATİCE | |
dc.contributor.author | DOĞAN ALİ | |
dc.contributor.author | YEGİN ZEYNEP ARZU | |
dc.contributor.author | KURT YÜKSEL MELTEM | |
dc.contributor.author | SADRİ SOĞOL | |
dc.contributor.author | YAVAŞOĞLU İRFAN | |
dc.contributor.author | Hüseyin Saffet Beköz | |
dc.contributor.author | Tekin Aksu | |
dc.contributor.author | Senem Maral | |
dc.contributor.author | Veysel Erol | |
dc.contributor.author | Leylagül Kaynar | |
dc.contributor.author | İLHAN OSMAN | |
dc.contributor.author | BOLAMAN ALİ ZAHİT | |
dc.contributor.author | SEVİNDİK ÖMÜR GÖKMEN | |
dc.contributor.author | AKYAY ARZU | |
dc.contributor.author | ÖZCAN MUHİT | |
dc.contributor.author | GÜRMAN GÜNHAN | |
dc.contributor.author | CANGÜL ÜNAL ŞULE | |
dc.contributor.author | YAVUZ YASEMİN | |
dc.contributor.author | KÜÇÜKKAYA DİZ REYHAN | |
dc.contributor.author | ÖZSAN GÜNER HAYRİ | |
dc.date.accessioned | 2023-06-22T09:34:21Z | |
dc.date.available | 2023-06-22T09:34:21Z | |
dc.date.issued | 2022 şubat | tr |
dc.identifier.citation | Sinem Civriz Bozdağ, Güldane Cengiz Seval, İpek Yönal Hindilerden, Fehmi Hindilerden, Neslihan Andıç, Mustafa Baydar, Lale Aydın Kaynar,et al. Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies. Turk J Haematol. 2022 Feb 23;39(1):43-54. | tr |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/13935 | |
dc.description.abstract | Objective: Patients with solid malignancies are more vulnerable to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection than the healthy population. The outcome of SARS-CoV-2 infection in highly immunosuppressed populations, such as in patients with hematological malignancies, is a point of interest. We aimed to analyze the symptoms, complications, intensive care unit admissions, and mortality rates of patients with hematological malignancies infected with SARS-CoV-2 in Turkey. Materials and Methods: In this multicenter study, we included 340 adult and pediatric patients diagnosed with SARS-CoV-2 from March to November 2020. Diagnosis and status of primary disease, treatment schedules for hematological malignancies, time from last treatment, life expectancy related to the hematological disease, and comorbidities were recorded, together with data regarding symptoms, treatment, and outcome of SARS-CoV-2 infection. Results: Forty four patients were asymptomatic at diagnosis of SARS CoV-2 infection. Among symptomatic patients, fever, cough, and dyspnea were observed in 62.6%, 48.8%, and 41.8%, respectively. Sixty nine (20%) patients had mild SARS-CoV-2 disease, whereas moderate, severe, and critical disease was reported in 101 (29%), 71 (20%), and 55 (16%) patients, respectively. Of the entire cohort, 251 (73.8%) patients were hospitalized for SARS-CoV-2. Mortality related to SARS-CoV-2 infection was 26.5% in the entire cohort; this comprised 4.4% of those patients with mild disease, 12.4% of those with moderate disease, and 83% of those with severe or critical disease. Active hematological disease, lower life expectancy related to primary hematological disease, neutropenia at diagnosis of SARS-CoV-2, ICU admission, and first-line therapy used for coronavirus disease-2019 treatment were found to be related to higher mortality rates. Treatments with hydroxychloroquine alone or in combination with azithromycin were associated with a higher rate of mortality in comparison to favipiravir use. Conclusion: Patients with hematological malignancy infected with SARS-CoV-2 have an increased risk of severe disease and mortality. | tr |
dc.language.iso | eng | tr |
dc.publisher | Turk J Hemato | tr |
dc.relation.isversionof | 10.4274/tjh.galenos.2021.2021.0287 | tr |
dc.rights | info:eu-repo/semantics/openAccess | tr |
dc.subject | COVID-19, SARS-CoV-2 infection, Hematological malignancy | tr |
dc.title | Clinical Characteristics and Outcome of COVID-19 in Turkish Hematological Malignancy Patients | tr |
dc.type | article | tr |
dc.relation.journal | Turk J Hemato | tr |
dc.contributor.department | Tıp Fakültesi | tr |
dc.identifier.volume | 39 | tr |
dc.identifier.endpage | 54 | tr |
dc.identifier.startpage | 43 | tr |
dc.relation.publicationcategory | Uluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanı | tr |