Determination of Serum Trace Elements and Oxidative Stress in Bitches with Transmissible Venereal Tumor
Abstract
Background: This study was conducted to compare the changes in oxidative stress levels with some trace elements in blood
serum in healthy bitches and bitches with transmissible venereal tumor (TVT).
Methods: A total of 40 bitches were used in the study. According to the genital organ examinations, healthy bitches constituted the
control group (n=20) and those with venereal tumors constituted the TVT group (n=20). Total oxidant status (TOS), total antioxidant
status (TAS) and oxidative stress index (OSI) were determined spectrophotometrically. In addition, some serum trace element
levels such as magnesium (Mg), manganese (Mn), iron (Fe), copper (Cu), zinc (Zn) and selenium (Se) were measured using an
ICP-MS analysis device.
Result: The serum Se, Mg and Zn levels were lower in the TVT group compared to the control group (p<0.01) and serum Fe and
Cu levels were higher in the TVT group than in the control group (p<0.01). Serum TOS and OSI levels were higher (p<0.001) and
serum TAS levels were lower (p<0.001) in the TVT group compared to the control group. The study results showed that oxidative
stress is high in bitches with TVT and in parallel with this, changes occur in the amount of certain trace elements that are associated
with oxidative stress.
Source
Indian Journal of Animal ResearchVolume
57Issue
8URI
https://arccjournals.com/journal/indian-journal-of-animal-research/BF-1615https://hdl.handle.net/20.500.12418/14298