| dc.description.abstract | Salvia cadmica is an endemic species known to have antioxidant, antimicrobial and aromatic
properties and the existence of Salvia species is known to date back to 753 BC. This species,
whose medicinal properties were first discovered by the Romans at this time, is used in a wide
variety of fields. Salvia species, which have a content especially rich in essential oils, are often
used in cosmetic, medical, and industrial fields. In addition, it has been shown by past studies
that the root parts of salvia species contain terpenoids, polyphenols and essential fatty acids.
Numerous cancer studies have been conducted with salvia species, and it seems that not enough
research has been done for salvia cadmica. In this study, IC50 values for Total Antioxidant
Status (TAS) were determined by ethanol extract taken from the above-ground parts of Salvia
cadmica. Then, using the MTT method, their cytotoxicity in the human colorectal
adenocarcinoma cancer cell line (HT-29) and healthy fibroblast cell line (L929) was
determined. Accordingly, Salvia Cadmica's IC50 dose was 64.22 ± 6.31 for the HT-29 cell line.
For healthy fibroblast cell lines, this ratio was higher than 400 μg/mL. | tr |
