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Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
(John Wiley & Sons Ltd, December 2)
Benzimidazole type N-heterocyclic carbene molecules and their metal complexes
have well-known biological activity. Elemental silver and silver complexes
also have antibacterial and antifungal activity. In this study, ...
A significant association between rs2295190 polymorphism of the ESR1 gene and fibromyalgia syndrome
(CMB Association Publiher, 2022)
Fibromyalgia syndrome (FMS) is a multifactorial disease characterized by chronic diffuse pain. Genetic
factors are also involved in the etiology. However, there is not enough information on the genetic factors
that ...
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
(28 Mart 20)
Rosemary officinalis L., Pelargonium graveolens L., and Mentha piperita L., essential oils are used by complementary medicine specialists simultaneously with traditional antibiotics for treatment purposes. The chemical ...
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
(De Gruyter, March 2022)
Abstract: Rosemary officinalis L., Pelargonium graveolens
L., and Mentha piperita L., essential oils are used by complementary
medicine specialists simultaneously with
traditional antibiotics for treatment purposes. The ...
Synergistic efficacy of meropenem, ciprofloxacin and colistin antibiotics against planktonic and biofilm forms of Myroides odoratimimus bacterial isolates
(Eylül 2022)
Purpose: In this study, it was aimed to investigate the combined synergistic efficacy of colistin (CT), meropenem (MEM), and ciprofloxacin (CIP) antibiotics on planktonic and biofilm forms in Myroidesodoratimimus strains ...
Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats
(Elsevier, 2022)
The toxicity of acetaminophen (N-acetyl-para-aminophenol (APAP)) is the most frequent cause of drug-induced liver damage. Galium aparine L. (GA) is traditionally used to treat jaundice. We aimed to investigate the ...
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)
Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ...
Synthesis, computational analyses, antibacterial and antibiofilm properties of nicotinamide derivatives
(Ağustos 20)
Newly designed nicotinamide derivatives were synthesized and characterized using spectral techniques (IR, 1H-NMR, 13C-NMR, and MS). Moreover, these compounds are investigated computationally. B3LYP/6–31 + G(d,p) level is ...
The 5-HT7 receptor antagonist SB-269970 alleviates seizure activity and downregulates hippocampal c-Fos expression in pentylenetetrazole-induced kindled rats
(NEUROLOGICAL RESEARCH, 2022)
Objectives: Recently, studies have demonstrated that serotonin type 7 receptors (5-HT7) have conflincting effects on neuronal excitability in different brain regions. However, the effect of 5-HT7 on seizures has not been ...
Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells
(Metabolic Brain Disease, 2022)
Recent studies have shown that angiotensin-converting enzyme (ACE) inhibitors have reduced oxidative damage in the central nervous system (CNS). Accumulating evidence have also demonstrated that captopril, an ACE inhibitor, ...