Browsing Cerrahi Tıp Bilimleri Bölümü by Author "0000-0003-0743-754X"
Now showing items 1-8 of 8
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Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia
Ozdemir, Ercan; Avcı, Onur; Sahin Inan, Zeynep Deniz; Taskiran, Ahmet Sevki; Güneş, Handan; Gursoy, Sinan (2023)Morphine is a drug used in chronic pain such as diabetic neuropathy, but the development of tolerance to its antinoci ceptive efect is an important clinical problem. Aspirin is an analgesic and antiapoptotic drug used in ... -
Cancer antigen-125 is a predictor of mortality in patients with pulmonary arterial hypertension
Şahin, Anıl; Kaya, Hakkı; Avcı, Onur (ELSEVIER, 2021)Background: Carbohydrate antigen 125 (CA 125), known as a tumor marker for ovarian cancer, has been reported to increase and be associated with severity in heart failure and chronic obstructive pulmonary disease. Patients ... -
Effect of adding dexmedetomidine to intra-articular levobupivacaine on postoperative pain following arthroscopic meniscus surgery: A prospective, double-blind, randomized, placebo- controlled, clinical trial
Avcı, Onur; Özdemir Kol, İclal; Gündoğdu, Oğuz; Öztemur, Zekeriya; Erşan, İdris (AVES Yayıncılık, 2021)Objective: The aim of this study was to determine the effect of adding dexmedetomidine to intra-articular levobupivacaine on postoperative pain levels and analgesic requirements following arthroscopic meniscectomy. Methods: ... -
Effect of captopril, an angiotensin-converting enzyme inhibitor, on morphine analgesia and tolerance in rats, and elucidating the inflammation and endoplasmic reticulum stress pathway in this effect
Taşkıran, Ahmet Şevki; Avcı, Onur (ELSEVIER, 2021)The purpose of current study was to examine the possible involvement of captopril, an angiotensin-converting enzyme inhibitor, on nociception, morphine analgesia and morphine tolerance development involving inflam mation ... -
Evaluation of the Effect of Interscalene Brachial Plexus Block on Intracranial Pressure Using Optic Nerve Sheath Diameter and Internal Jugular vein Collapsibility Index
Gündoğdu, Oğuz; Avcı, Onur (Journal of the College of Physicians and Surgeons Pakistan, 2022)Objective: To determine the effect of single-shot interscalene brachial plexus (ISBP) block on intracranial pressure (ICP) by eval uating the extravascular volume effect of the medicine on the internal jugular vein ... -
Metformin prevents morphine‑induced apoptosis in rats with diabetic neuropathy: a possible mechanism for attenuating morphine tolerance
Avcı, Onur; Ozdemir, Ercan; Taskiran, Ahmet Sevki; Sahin Inan, Zeynep Deniz; Gursoy, Sinan (Springer, 2022)Morphine is a drug of choice for the treatment of severe and chronic pain, but tolerance to the antinociceptive efect limits its use. The development of tolerance to morphine has recently been associated with neuronal ... -
Relationship between Systemic Immune-inflammation Index and Mortality in Intensive Care Patients Diagnosed with Crimean-Congo Hemorrhagic Fever
Gündoğdu, Oğuz; Avcı, Onur (Journal of the College of Physicians and Surgeons Pakistan, 2022)Objective: To evaluate the power of the systemic immune-inflammation index in the prediction of mortality in severe Crimean--Congo hemorrhagic fever patients. Study Design: Observational study. Place and Duration of ... -
The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19
Bagci, Gökhan; Gündoğdu, Oğuz; Pektaş, Ayşe Nur; Bağci, Binnur; Avcı, Onur; Gursoy, Sinan; Kaygusuz, Kenan; Elaldı, Nazif (2023)Toll-like receptors (TLRs) recognize infectious agents and play an important role in the innate immune system. Studies have suggested that TLR single nucleotide polymorphisms (SNPs) are associated with poor antiviral ...