Browsing Cerrahi Tıp Bilimleri Bölümü Makale Koleksiyonu by Author "0000-0003-4725-043X"
Now showing items 1-17 of 17
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Anticancer activity of Heat Shock Protein 70 (HSP70) Inhibitor, JG-98, against human cervical cancer HeLa and ovarian cancer SKOV-3 cells
YURTCU, Nazan; KARADEMİR, Dilay; Ergül Mustafa; Çetin, Ali; Tinelli, Andrea (Medicine Science International Medical Journal, 2023/3/1)Abstract Cervical and ovarian cancer are two aggressive neoplasms for women, still with high mortality and morbidity. Among the molecules and compounds that have anticancer activity, it was studied the JG-98, a heat shock ... -
Assessment of vaginal and endometrial microbiota by real‐time PCR in women with unexplained infertility
Sezer, Özlem; Caliskan, Canan; Çelik, Samettin; Kılıç, Süleyman Sırrı; Kuruoglu, Tuba; Unluguzel Ustun, Goksenin (2022/1)Abstract Aim Microbiota of the reproductive tract may be associated with unexplained infertility in women. We aimed to determine the derangements of vaginal and endometrial microbiota related to unexplained infertility ... -
Autoimmune Pathogenesis, Related Diseases and Laboratories
Yurtcu, Nazan; Demir, Kenan (01/08/2021)The immune system is a complex system that forms the defense mechanism against diseases in a living thing, recognizes and destroys pathogens and tumor cells, and protects the body from foreign and harmful substances. ... -
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
YARŞILIKAL, GÜLEROĞLU FİLİZ; SELVİ, ESRA; TURAN, BAKIRCI ISIL; Bafalı, Olgu; Argun Atalmış, Hatice; YASTI DAYAN, MERVE; BALKAN, ÖZMEN ALİYE; YURTCU, NAZAN; Seker Atas, Busra; Özdemir Anayurt, Esma; ÇETİN, ALİ (2023/2)Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension (GHT). Methods ... -
Clinical value of serum BMP-4, BMP-2, GDF-15, MMP-9, GP39 levels in pregnant women with obesity and the related comorbidities diabetes mellitus and gestational hypertension
YURTCU, Nazan; Yarsilikal Guleroglu, Filiz; Selvi, Esra; uran Bakirci, Isil; Bafaloı, Olgu; Argun Atalmis, Hatice; Çetin, Ali (Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany, 2023/2)Abstract Aims We evaluated the clinical value of selected serum biomarkers BMP-4, BMP-2, GDF-15, MMP-9, and GP39 in pregnant women with obesity and the comorbidities diabetes mellitus (DM) and gestational hypertension ... -
Derangements of vaginal and cervical canal microbiota determined with real-time PCR in women with recurrent miscarriages
Caliskan, Canan; Yurtcu, Nazan; Çelik, Samettin; Sezer, Özlem; Kılıç, Süleyman Sırrı; Çetin, Ali (2022/8/18)Balanced vaginal microbiota and, as a continuum, cervical canal microbiota help prevent reproductive disorders, including recurrent miscarriage (RM). In a significant proportion of couples with RM, routine diagnostic workup ... -
Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
YURTCU, Nazan; Sönmez Ünal, Gamze; Albak, Yasemin; Yıldız, Çağlar; Çetin, Meral; DURNA DAŞTAN, SEVGİ (Galenos Yayinevi Tic. Ltd., Eylül/2023)Objective This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods Five groups were formed with eight ... -
Prediction of gestational diabetes mellitus and perinatal outcomes by plasma zonulin levels
Oral, Serkan; Çelik, Sebahattin; Akpak, Yasam Kemal; Golbasi, Hakan; Bayraktar, Burak; Unver, Gokhan; Sahin, Sami; Yurtcu, Nazan; Caliskan, Canan (2022/8/22)Abstract Purpose: Zonulin has been shown to be associated with many metabolic disorders, including type 2 diabetes mellitus, metabolic syndrome, and obesity. In this study, we aimed to evaluate the association between ... -
Predictive and Diagnostic Value of Serum Adipokines in Pregnant Women with Intrahepatic Cholestasis
Yurtcu, Nazan; Caliskan, Canan; Güney, Huri; Çelik, Samettin; Hatırnaz, Şafak; Tinelli, Andrea (2022/2/16)The objective of this study was to assess the value of serum leptin, adiponectin, apelin, and ghrelin as biomarkers for the prediction and diagnosis of intra-hepatic cholestasis (ICP). This prospective study included ... -
Predictive and diagnostic value of serum sVEGFR-1 level in women with preeclampsia: A prospective controlled study
Salk, Sultan; YURTCU, Nazan; Çetin, Ali (2022/12)Abstract Objective: Pre-eclampsia (PE), a pregnancy-specific syndrome consisting of hypertension and proteinuria occurring de novo after the 20th week of gestation, remains the leading cause of maternal and fetal morbidity ... -
Predictive and Prognostic Value of Plasma Zonulin for Gestational Diabetes Mellitus in Women at 24–28 Weeks of Gestation
Yılmaz Zehra; Oral, Serkan; Yurtcu, Nazan; Akpak, Yasam Kemal; Çelik, Sebahattin; Caliskan, Canan (2022/12)Objective We aimed to examine the predictive and prognostic value of plasma zonulin for gestational diabetes mellitus (GDM) in women at 24–28 weeks of gestation. Methods This retrospective study was carried out with ... -
Predictive value of pregnancy of follicular fluid fetuin-A and-B levels in infertile women after intra-cytoplasmic sperm injection
Yurtcu, Nazan (2021/12)AimWe aimed to investigate the value of follicular fluid Fetuins-A and -B to predict successful IVF and pregnancy outcomes in infertile women with poor, normal, and high ovarian reserve. MethodsThe follicular fluid of 96 ... -
Relationship between serum cadherin 6 and 11 levels and severe and early-onset preeclampsia: A pilot study
Güney, Huri; Caliskan, Canan; Çelik, Samettin; Yurtcu, Nazan; Hatırnaz, Şafak; Avcı, Bahattin; Tinelli, Andrea (2022/6)Abstract Objective: Preeclampsia is a highly morbid disease of placental origin, life-threatening condition for both a pregnant woman and her fetus. Cadherin 6 and 11 are adhesion molecules that play an important role ... -
Serum Melatonin as a Biomarker for Assessment of Late-term and Postterm Pregnancies in Women without Spontaneous Onset of Labor
Yurtcu, Nazan; Çalışkan, Canan; Çelik, Samettin (Georg Thieme Verlag KG, 2021/12)We conducted a prospective study to assess serum melatonin as a biomarker to predict the development of late-term and postterm pregnancies and spontaneous beginning of labor in women with term pregnancies. Population of ... -
The effect of embryo transfer technique on pregnancy and live birth rates in infertile women undergoing IVF treatment with freeze-all strategy
Abstract Objective: The aim of this observational retrospective cohort study was to define the effect of the embryo transfer (ET) technique on pregnancy and live birth rates. Material and Methods: Infertile women with ... -
The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum
YURTCU, Nazan; KARADEMİR, Dilay (2023/9/30)ABSTRACT History Received: 11/04/2023 Accepted: 22/09/2023 Hyperemesis gravidarum (HG) has severe, dramatic consequences, and the cause of this severe disease has not yet been determined clearly. It is known that ... -
Zonulin as a potential biomarker for diminished ovarian reserve: A prospective study
YURTCU, Nazan; Çelik, Sebahattin; Caliskan, Canan; Çelik, Samettin (2023/6)Objective: The purpose of this research is to investigate the relationship between zonulin levels and diminished ovarian reserve (DOR), and to evaluate the potential role of autoimmunity in the development of DOR. The ...