Yayın tarihi için Klinik Öncesi Bilimleri Bölümü listeleme
Toplam kayıt 87, listelenen: 1-20
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The Effects of Sunitinib in Healthy and Cisplatin-Induced Rats
(04.01.2023)Sunitinib is a multitargeted kinase inhibitor that inhibits many receptor tyrosine kinases and has been used in the treatment of gastrointestinal stromal tumors, metastatic renal cell carcinoma, and pancreatic neuroendocrine ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
(05/05/2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Lipid-lowering, antiinflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice
(05/2023)Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen (APAP) induced hepatotoxicity is still ... -
Phenolic profile and investigation of biological activities of Allium scorodoprasum L. subsp. rotundum
(06/01/2022)In this study, phenolic profile of Allium scorodoprasum L. subsp. rotundum and its bioactivity in multiway approach including antioxidant, antimicrobial, antidiabetic, cytotoxic and antiinflamatory activities were investigated. ... -
The effects of sorafenib in healthy and cisplatin-treated rats
(07.10.2023)Background. Sorafenib is a multikinase inhibitor currently used in the treatment of hepatocellular carcinoma, renal cell carcinoma and thyroid cancer. Objectives. The literature on this agent is scarce. This study aimed ... -
Kaempferol and Isorhamnetin alleviate Lipopolysaccharide-Induced Anxiety and Depression-Like Behavioral in Balb/C Mice
(09/07/2023)The etiology of anxiety and depression is linked to inflammation and oxidative stress. Isorhamnetin and Kaempferol are strong antioxidants with anti-inflammatory neuroprotective properties. This study, it was aimed to ... -
Pharmacokinetics of meloxicam following intravenous administration at different doses in sheep
(13/09/2023)The aim of this study is to determine the pharmacokinetic change after intravenous administration of meloxicam at doses of 0.5, 1 and 2 mg/kg to sheep. The study was carried out on six Akkaraman sheep. Meloxicam was ... -
Mechanism of anticancer effect of gambogic acid on gastric signet ring cell carcinoma
(16.08.2023)Gambogic acid has demonstrated inhibitory effects on the growth of various cancer cell types, such as breast cancer, pancreatic cancer, prostate cancer, lung cancer, and osteosarcoma. This study aims to investigate the ... -
The First Molecular Detection of Two Gyroviruses (Chicken Anemia Virus and Gyrovirus galga 1) from Domestic Cats in Turkey
(17.03.2022)Gyroviruses are one of 31 genera in the family Anelloviridae. The prototype of the gyrovirus genus is Chicken anemia virus (CAV). There are 9 other species in this genus besides CAV. Gyroviruses are small, single- stranded ... -
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
(20.02.2023)Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ... -
Molecular detection and characterization of infectious laryngotracheitis virus in backyard chickens in Turkey
(Afyon Kocatepe Üniversitesi, 2020)Gallid herpesvirus I (GaHV1) is etiological agent of infectious laryngotracheitis (ILT) and ILT is one of the important disease that included in respiratory infections of chickens. Few studies have been conducted in Turkey ... -
Intestinal system helminths of red foxes and molecular characterization Taeniid cestodes
(Springer Link, 2021)Red foxes (Vulpes vulpes) are the most prevalent wild carnivores in the world and definitive hosts of many pathogenic parasites for humans and farm animals. These animals travel great distances in search of prey and nests, ... -
Updated checklist of Culicoides Latreille (Diptera: Ceratopogonidae) of Turkey with ten new records
(BioOne Complete, 2021)We investigated the Culicoides fauna in Turkey during the years 2016-2019 in the process of entomological surveillance for arboviral diseases. The entomological survey was conducted at 104 sampling ... -
MOLECULAR PREVALENCE OF CANINE HEPATOZOONOSIS IN OWNED-DOGS IN CENTRAL PART OF TURKEY
(2021)Canine hepatozoonosis is a tick-borne disease caused by Hepotozoon canis and Hepotozoon americanum. H. canis is widespread almost all over the world, while H. americanum exists only in the continental of America. The ... -
First Parasitological Data on a Wild Grey Wolf in Turkey with Morphological and Molecular Confirmation of the Parasites
(Springer Link, 2021)Introduction The grey wolf (Canis lupus) is the natural host of many parasites. These animals travel quite long distances to search for prey and nests, causing parasites to spread over large areas; therefore, determination ... -
The detection and phylogenetic analysis of Anaplasma phagocytophilum-like 1, A. ovis and A. capra in sheep: A. capra divides into two genogroups.
(2022)In this study, the presence, prevalence, and genotypes of Anaplasma phagocytophilum, A. ovis, and A. capra in sheep were investigated based on 16 S SSU rRNA, groEL, and gtlA gene-specific polymerase chain reaction (PCR), ... -
Buffaloes as new hosts for Anaplasma capra: Molecular prevalence and phylogeny based on gtlA, groEL, and 16S rRNA genes
(Elsevier, 2022)Anaplasma capra is a tick-borne pathogen that was discovered for the first time in goats in China in 2012. The studies carried out from the first detection in China to the present have revealed the presence of this species ... -
Buffaloes as new hosts for Anaplasma capra: Molecular prevalence and phylogeny based on gtlA, groEL, and 16S rRNA genes
(2022)Anaplasma capra is a tick-borne pathogen that was discovered for the first time in goats in China in 2012. The studies carried out from the first detection in China to the present have revealed the presence of this species ... -
The first molecular detection of Anaplasma capra in domestic ruminants in the Central Part of Turkiye, with genetic diversity and genotyping of Anaplasma capra
(Springer Link, 2022)Tick-borne diseases have been an increasing threat to human and animal health all over the world. Anaplasmosis, is one of the emerging-tick borne diseases, has zoonotic potential. A new novel species, which was detected ... -
First Molecular Detection of Anaplasma Species in cattle from Kyrgyzstan; molecular identification of human pathogenic novel genotype Anaplasma capra and Anaplasma phagocytophilum related strain
(Elsevier, 2022)Anaplasmosis is a rickettsial infection with significant effects on human and animal health, and the discovery of new species or genotypes with zoonotic potential in recent years has increased this importance. The aim of ...