Browsing Temel Tıp Bilimleri Bölümü Makale Koleksiyonu by Author "284ecb9f-1b1c-4d3b-b993-b2a4ce5258cb"
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ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
Tutar, Uğur; Çelik, Cem; Şahin, Neslihan (April 2022)Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is aimed ... -
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
Çelik, Cem; Şahin, Neslihan; Üstün, Elvan; Tutar, Uğur; Gürbüz, Nevin; Özdemir, İsmail (Elsevier, 15/09/2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were characterized ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
Çelik, Cem; Üstün, Elvan; Şahin, Neslihan; Tutar, Uğur (John Wiley & Sons Ltd, December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
Çelik, Cem; Tutar, Uğur; Şahin, Neslihan; Öztürk, Ayşegül (April 2022)Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential ... -
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
Tutar, Uğur; Çelik, Cem; Üstün, Elvan; Özdemir, Namık; Şahin, Neslihan; Semeril, David; Gürbüz, Nevin; Özdemir, İsmail (27 Septemb)Abstract Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1-methallyl-3-(3,4,5-tr ... -
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
Dinçer, Emine; Işık, Hakan; Hepokur, Ceylan; Tutar, Uğur; Çelik, Cem (Haziran 20)ABSTRACT Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to ...