Browsing Temel Tıp Bilimleri Bölümü Makale Koleksiyonu by Author "0000-0002-7141-5874"
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ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
Tutar, Uğur; Çelik, Cem; Şahin, Neslihan (April 2022)Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is aimed ... -
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
Çelik, Cem; Şahin, Neslihan; Üstün, Elvan; Tutar, Uğur; Gürbüz, Nevin; Özdemir, İsmail (Elsevier, 15/09/2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were characterized ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
Çelik, Cem; Üstün, Elvan; Şahin, Neslihan; Tutar, Uğur (John Wiley & Sons Ltd, December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
Taşkın Kafa, Ayşe Hümeyra; Aslan, Rukiye; Çelik, Cem; Hasbek, Mürşit (De Gruyter, March 2022)Abstract: Rosemary officinalis L., Pelargonium graveolens L., and Mentha piperita L., essential oils are used by complementary medicine specialists simultaneously with traditional antibiotics for treatment purposes. The ... -
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
Çelik, Cem; Tutar, Uğur; Şahin, Neslihan; Öztürk, Ayşegül (April 2022)Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
Çelik, Cem; Üstün, Elvan; Şahin, Neslihan; Tutar, Uğur; Özdemir, Namık; Gürbüz, Nevin; Özdemir, İsmail (The Royal Society of Chemistry, 2 November)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ...