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SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia
(TAYLOR & FRANCIS INC, 2017)
Objective: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE).Methods: In total, 89 ...
Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women
(WILEY, 2007)
Aim: To assess the association between human epoxide hydrolase exon 3 and 4 polymorphisms and pre-eclampsia by carrying out a case-control study in Turkish women. Methods: DNA was extracted from peripheral blood leukocytes, ...
Strong association between lung cancer and the AXIN2 polymorphism
(SPANDIDOS PUBL LTD, 2009)
Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes to carcinogenesis. The effect of the AXIN2 ...
Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women
(ELSEVIER SCIENCE BV, 2006)
Objectives: It is possible that altered control of aldosterone synthase gene (CYP11B2) expression or translation may be responsible for. hypertension. Hypertension is one of the major components of preeclampsia. We present ...
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
(SPANDIDOS PUBL LTD, 2011)
Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ...
The evaluation of two genetic polymorphisms of paraoxonase 1 in patients with pulmonary embolism
(WILEY, 2018)
Background and ObjectivePulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti-oxidative and anti-inflammatory effects. According to our knowledge, ...
ANALYSIS OF IL-6, IL-10 AND NF-kappa B GENE POLYMORPHISMS IN AGGRESSIVE AND CHRONIC PERIODONTITIS
(NATL INST PUBLIC HEALTH, 2017)
Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-kappa B(NF-kappa B). The aim of this ...
VITAMIN D RECEPTOR TAQI POLYMORPHISM IS ASSOCIATED WITH HIGHER IMMUNE RESPONSE TO HEPATITIS B VACCINATION IN TURKISH DIALYSIS PATIENTS
(CARBONE EDITORE, 2018)
Introduction: We aimed to investigate the possible role of vitamin D receptor (VDR) gene TaqI, ApaI and FokI polymorphisms in immune response to Hepatitis B virus (HBV) vaccination in dialysis patients. Methods: A total ...
Lack of Association between the MTHFR C677T Polymorphism and Lung Cancer in a Turkish Population
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)
Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ...
Angiotensin-Converting Enzyme (ACE) I/D and Alpha-Adducin (ADD1) G460W Gene Polymorphisms in Turkish Patients with Severe Chronic Tinnitus
(AVES, 2016)
OBJECTIVE: Tinnitus is described as a disturbing sound sensation in the absence of external stimulation. We aimed to investigate whether there is any relationship between severe chronic tinnitus and angiotensin-converting ...