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The CYP4502D6*4 and*6 alleles are the molecular genetic markers for drug response: implications in colchicine non-responder FMF patients
(SPRINGER FRANCE, 2016)
The cytochrome P450 2D6 (CYP2D6) is a cytochrome P450 enzyme involved in the oxidative biotransformation of the xenobiotics, carcinogens and various clinically important drugs. Patients are evaluated in three sub-groups ...
Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Invasive ductal carcinoma is the most common breast malignancies tumors and has tendency to bone metastases. Many oncogenic client proteins involved in formation of metastatic pathways. Stabilization, regulation, and ...
Effect of increasing maximal aerobic exercise on serum gonadal hormones and alpha-fetoprotein in the luteal phase of professional female soccer players
(SOC PHYSICAL THERAPY SCIENCE, 2016)
[Purpose] The performance of female athletes during their menstrual period has attracted the attention of researchers for many years. It is known that the menstrual period changes with exercise. Alpha-fetoprotein (AFP) is ...
Compactness of the set of trajectories of the control system described by a Urysohn type integral equation with quadratic integral constraints on the control functions
(SPRINGER INTERNATIONAL PUBLISHING AG, 2016)
In this paper the control system is considered described by a Urysohn type integral equation which is nonlinear with respect to the state vector and is affine with respect to the control vector. The functions from the space ...
The nucleophilicity equalization principle and new algorithms for the evaluation of molecular nucleophilicity
(ELSEVIER SCIENCE BV, 2016)
In this work, we have attempted to explore whether the nucleophilicity equalization principle can be conceived analogous to the well-established electronegativity, hardness, and electrophilicity equalization principle. ...
Assessment of Hematological Factors Involved in Development and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss
(LIPPINCOTT WILLIAMS & WILKINS, 2016)
Objective: The aim of this study was to investigate the possible effects of routine hematological parameters on the development and prognosis of idiopathic sudden sensorineural hearing loss in patients applying to our ...
BODIPY based self-healing fluorescent gel formation via acylhydrazone linkage
(ROYAL SOC CHEMISTRY, 2016)
Polymeric BODIPY derivatives with reactive functional groups undergo reversible formation of covalent bonds leading to self-healing properties. Cross-reactivity of acyl-hydrazine and aldehyde moieties forms the basis of ...
Crustal thickness variations in the Eastern Mediterranean and southern Aegean region
(ELSEVIER SCI LTD, 2016)
In this paper, regional analog gravity anomaly map obtained from the General Directorate of Mineral Research and Exploration (MTA) was digitized and used for the calculation of the crustal thickness (Moho depth) variations ...
The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis
(WILEY, 2016)
Background: The aim of this study examines the effect of systemic melatonin administration on proin-flammatory cytokine levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with ...
Treatment of automotive industry wastewater using anaerobic batch reactors: The influence of substrate/inoculum and molasses/wastewater
(INST CHEMICAL ENGINEERS, 2016)
A study of the anaerobic treatment of an automotive-industry wastewater was conducted at mesophilic temperature in batch mode. In this study, molasses was used as a co-substrate. The experiments were carried out with samples ...