Search
Now showing items 1-10 of 32
Beneficial effects of quercetin on rat urinary bladder after spinal cord injury
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)
Background: Spinal cord injury (SCI) leads to an inflammatory response and generates oxidative stress, which has deleterious effects on the function of several organ systems, including the urinary bladder. The present study ...
The preventive and curative effects of melatonin against abdominal aortic aneurysm in rats
(MOSBY-ELSEVIER, 2018)
Objective: Oxygen free radicals are important components involved in the histopathologic tissue alterations observed during abdominal aortic aneurysms (AAAs). This study examined whether melatonin has protective or therapeutic ...
Cyclosporine-A induces apoptosis in human prostate cancer cells PC3 and DU145 via downregulation of COX-2 and upregulation of TGF beta
(WALTER DE GRUYTER GMBH, 2019)
Background: Potential targets for prostate cancer therapy are urgently needed for curative of patients. Cyclosporine-A (CsA), an immunosuppressive and a selective cyclooxygenase-2 (COX-2) inhibitor, exerts antitumor activity. ...
Antioxidant Agent Quercetin Prevents Impairment of Bladder Tissue Contractility and Apoptosis in a Rat Model of Ischemia/Reperfusion Injury
(WILEY, 2017)
ObjectivesTo examine the possible protective effect of quercetin (QT), which is well known for its antioxidant and protective effects in circumstances of oxidative stress, on urinary bladder tissue in a rat model of ...
Effects of Riboflavin on Traumatic Brain Injury Induced in Rats
(WILEY-BLACKWELL, 2016)
…
Investigation into the role of the cholinergic system in radiation-induced damage in the rat liver and ileum
(OXFORD UNIV PRESS, 2014)
It has been previously shown that acetylcholine (ACh) may affect pro-inflammatory and anti-inflammatory cytokines. The role of the cholinergic system in radiation-induced inflammatory responses and tissue damage remains ...
Mycophenolate mofetil attenuates uterine ischaemia/reperfusion injury in a rat model
(ELSEVIER SCI LTD, 2017)
This study evaluated the effect of mycophenolate mofetil (MMF) on uterine tissue preservation following ischaemia/reperfusion (I/R) injury. Uterine I/R injury was induced in rats by clamping the lower abdominal aorta and ...
Synthesis, Cytotoxicity, and Pro-Apoptosis Activity of Etodolac Hydrazide Derivatives as Anticancer Agents
(WILEY-V C H VERLAG GMBH, 2013)
Etodolac hydrazide and a novel series of etodolac hydrazide-hydrazones 315 and etodolac 4-thiazolidinones 1626 were synthesized in this study. The structures of the new compounds were determined by spectral (FT-IR, 1H NMR, ...
The apoptotic actions of platelets in acute ischemic stroke
(SPRINGER, 2013)
Stroke is a disease that affects the blood vessels that supply blood to the brain. Although platelets are implicated in the pathophysiology of stroke the mechanism is still not clear and there antiplatelet agents available ...
Melatonin and tadalafil treatment improves erectile dysfunction after spinal cord injury in rats
(WILEY, 2014)
Oxidative stress plays an important role both in spinal cord injury (SCI) and erectile dysfunction (ED). The present study investigated the effects of melatonin and tadalafil treatment alone or in combination on SCI-induced ...