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Tumor necrosis factor-alpha induced caspase-3 activation-related iNOS gene expression in ADP-activated platelets
(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2017)
Platelets are sensitive cells and are easily activated by different stimulants in the circulation system. It is known that tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine and plays a role in inflammation. ...
N-acetylcysteine leads to greater ovarian protection than enoxaparin sodium in a rat ovarian torsion model
(ELSEVIER SCI LTD, 2016)
This study evaluated the effects of N-acetylcysteine (NAC) and enoxaparin on ovarian tissue preservation, ovarian reserve and oxidative damage following ovarian torsion/detorsion injury. Rats were divided into four groups ...
Platelets Proteomic Profiles of Acute Ischemic Stroke Patients
(PUBLIC LIBRARY SCIENCE, 2016)
Platelets play a crucial role in the pathogenesis of stroke and antiplatelet agents exist for its treatment and prevention. Through the use of LC-MS based protein expression profiling, platelets from stroke patients were ...
Interferon regulatory factor 5 (IRF5) suppresses hepatitis C virus (HCV) replication and HCV-associated hepatocellular carcinoma
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2017)
Hepatitis C virus (HCV) infection is a major risk factor for the development of chronic liver disease. The disease typically progresses from chronic HCV to fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and death. ...
Ameliorative effects of riboflavin on acetic acid-induced colonic injury in rats
(WILEY, 2018)
Riboflavin (RF) has been found to be a promising antioxidant and/or anti-inflammatory agent in several studies. However, the effect of RF against acetic acid (AA)-induced colonic injury is currently unknown. This study ...
Synthesis of Diflunisal Thiazolidinones as Anticancer Agents
(BENTHAM SCIENCE PUBL LTD, 2016)
A series of diflunisal 4-thiazolidinones were synthesized. Some selected compounds were determined at one dose towards the full panel of 60 human cancer cell lines by National Cancer Institute. 2',4'-Difluoro-4-hydroxy-N ...
Effects of Alendronate on Kidney Tissue of Ovariectomized Rats
(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2013)
Alendronate is an aminophosphanate, selective inhibitory of bone resorbtion, used for treatment of osteoporosis in postmenopause. It is known that changes occurring in postmenopausal period effect the quality of life. In ...
Novel adipokines WISP1 and betatrophin in PCOS: relationship to AMH levels, atherogenic and metabolic profile
(TAYLOR & FRANCIS LTD, 2017)
Objective: To determine the levels of WISP1 and betatrophin in normal weight and obese women with polycystic ovary syndrome (PCOS) and to assess their relationship with anti-Mullerian hormone (AMH) levels, atherogenic ...
WISP1 is a novel adipokine linked to metabolic parameters in gestational diabetes mellitus
(TAYLOR & FRANCIS LTD, 2017)
Objective: To investigate Wnt1-inducible signaling pathway protein-1 (WISP1) levels and their correlation with metabolic parameters in pregnant women with gestational diabetes mellitus (GDM) and non-GDM healthy pregnant ...
Effects of Myrtus communis extract treatment in bile duct ligated rats
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2016)
Background: The aim of our study was to investigate the antifibrotic and antioxidant effects of Myrtus communis subsp. communis (MC) extract against liver injury and fibrosis occurring in rats with biliary obstruction. ...