Search
Now showing items 1-10 of 13
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
(SPANDIDOS PUBL LTD, 2011)
Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ...
The evaluation of two genetic polymorphisms of paraoxonase 1 in patients with pulmonary embolism
(WILEY, 2018)
Background and ObjectivePulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti-oxidative and anti-inflammatory effects. According to our knowledge, ...
ANALYSIS OF IL-6, IL-10 AND NF-kappa B GENE POLYMORPHISMS IN AGGRESSIVE AND CHRONIC PERIODONTITIS
(NATL INST PUBLIC HEALTH, 2017)
Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-kappa B(NF-kappa B). The aim of this ...
Lack of Association between the MTHFR C677T Polymorphism and Lung Cancer in a Turkish Population
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)
Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ...
Angiotensin-Converting Enzyme (ACE) I/D and Alpha-Adducin (ADD1) G460W Gene Polymorphisms in Turkish Patients with Severe Chronic Tinnitus
(AVES, 2016)
OBJECTIVE: Tinnitus is described as a disturbing sound sensation in the absence of external stimulation. We aimed to investigate whether there is any relationship between severe chronic tinnitus and angiotensin-converting ...
Polymorphisms of selected genes related to increased cardiovascular risk in patients with acute coronary syndromes and their relation to the severity of coronary artery disease
(TERMEDIA PUBLISHING HOUSE LTD, 2012)
Background: beta-Fibrinogen 455G/A, factor V 1691G/A, 1299H/A and glycoprotein Ilb/IIla PL A1/A2 polymorphisms are tought to be related to arterial thrombotic disorders, especially coronary artery disease (CAD) and myocardial ...
Studying the Association between Sudden Hearing Loss and DNA N-Methyltransferase 1 (DNMT1) Genetic Polymorphism
(AVES, 2017)
OBJECTIVE: The aim of the present study was to investigate whether there was any relationship between some DNA N-methyltransferase 1 (DNMT1) polymorphisms and susceptibility to idiopathic sudden sensorineural hearing loss ...
Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015)
Objective: In this case-control study, we investigated whether IL-6 (-174G/C) and TNF-alpha (-308G/A) gene polymorphisms affect the clinical course and outcome of CCHF. Methods: Total 150 patients with CCHF and 170 controls ...
Microsomal epoxide hydrolase polymorphisms
(SPANDIDOS PUBL LTD, 2010)
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change ...
Glutathione-S-Transferase Variants are not Associated With Increased Carotid Intima-Media Thickness in Turkish Familial Mediterranean Fever Patients
(TURKISH LEAGUE AGAINST RHEUMATISM, 2016)
Objectives: This study aims to evaluate the carotid intima-media thickness (CIMT) in patients diagnosed with familial Mediterranean fever (FMF) and investigate whether there is a relationship between glutathione-S-transferase ...