Browsing Temel Eczacılık Bilimleri Bölümü Makale Koleksiyonu by Author "92751ebf-d6a5-4250-94a4-edcd23dbc2ed"
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Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
Işık, Ayşen; Çevik, Ulviye Acar; Çelik, İsmail; Bostancı, Hayrani Eren; Karayel, Arzu; Gündoğdu, Gülsüm; İnce, Ufuk; Koçak, Ahmet; Özkay, Yusuf; Kaplancıklı, Zafer Asım (Elsevier, 14.08.2022)Based on the biologically active heterocycle compounds, a series of new benzimidazole-hydrazone deriva- tives ( 3a-3j ) were synthesized, starting from 4-(6-chloro-1 H -benzimidazol-2-yl) benzohydrazide. The syn- thesized ... -
Synthesis, Molecular Docking, Dynamics, Quantum-Chemical Computation, and Antimicrobial Activity Studies of Some New Benzimidazole−Thiadiazole Hybrids
Çelik, İsmail; Çevik, Ulviye Acar; Karayel, Arzu; Işık, Ayşen; Kayış, Uğur; Gül, Ülküye Dudu; Bostancı, Hayrani Eren; Konca, Süheyl Furkan; Özkay, Yusuf; Kaplancıklı, Zafer Asım (ACS, 09.11.2022)In this study, some new compounds, which are 2aminothiadiazole derivatives linked by a phenyl bridge to the 2position of the benzimidazole ring, were designed and synthesized as antimicrobial agents. The structures of ...