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Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
(Elsevier, 14.08.2022)
Based on the biologically active heterocycle compounds, a series of new benzimidazole-hydrazone deriva-
tives ( 3a-3j ) were synthesized, starting from 4-(6-chloro-1 H -benzimidazol-2-yl) benzohydrazide. The syn-
thesized ...
Synthesis, and docking studies of novel tetrazole S-alkyl derivatives as antimicrobial agents
(Taylor & Francis, 01.09.2022)
A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their
antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC
22019) and ...
Synthesis, Molecular Docking, Dynamics, Quantum-Chemical Computation, and Antimicrobial Activity Studies of Some New Benzimidazole−Thiadiazole Hybrids
(ACS, 09.11.2022)
In this study, some new compounds, which are 2aminothiadiazole
derivatives linked by a phenyl bridge to the 2position
of the benzimidazole ring, were designed and synthesized
as antimicrobial agents. The structures of ...
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
(Medicinal Chemistry Research, 08.08.2022)
In this study, eleven new compounds with a series of benzimidazole-1,3,4-oxadiazole derivatives structures were
synthesized and evaluated for their human (h) carbonic anhydrase inhibitory activities against two isoforms ...