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Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
(Elsevier, 2022/09/15)
Design, synthesis, structural elucidation, and investigation of cytotoxic and antimicrobial activity,
butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) enzyme inhibition effects of isatinthiosemicarbazone ...
Potential thiosemicarbazone‐based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations
(Taylor & Francis, 2022/01/26)
A new series of thiosemicarbazone derivatives (1–11) were prepared from various
aldehydes and isocyanates with high yields and practical methods. The structures of
these compounds were elucidated by Fourier transform ...
1, 2, 3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
(Taylor & Francis, 2022/01/26)
In recent years, acetylcholinesterase (AChE) and α-glycosidase (α-gly) inhibition have emerged as a promising and important approach for pharmacological intervention in many diseases such as glaucoma, epilepsy, obesity, ...
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
(Elsevier, 2022/12/05)
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds ...
Synthesis and biological evaluation of thiosemicarbazone derivatives
(Springer US, 2022/07/21)
In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were ...
Biological effects and molecular docking studies of Catechin 5-O-gallate: Antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
(Taylor & Francis, 2022/04/13)
Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ...
Phthalocyanine complexes with (4-isopropylbenzyl) oxy substituents: preparation and evaluation of anti-carbonic anhydrase, anticholinesterase enzymes and molecular docking studies
(Taylor & Francis, 2022/01/26)
n this study, the preparation, aggregation behavior and investigation of carbonic anhydrase and cholinesterase enzyme inhibition features of non-peripherally (4-isopropylbenzyl)oxy-substituted phthalocyanines (4–6) are ...
The synthesis and characterization of iron nanoparticles with lemon peel and its use in magnetic solid phase extraction for trace levels of lead (II)
(Springer, 03/03/2022)
In this study, a new magnetic solid phase extraction method (MSPE) was developed for the enrichment and separation of
trace amount Pb(II) on the magnetic nanoparticles synthesized using lemon peel (
Fe3O4-LP). The ...
Development of quantum dot-phthalocyanine integrated G-quadruplex /double-stranded DNA biosensor
(Elsevier, 2022)
In the present study, the phthalocyanine (Pc) integrated mercaptopropionic acid capped quantum dot
(mpa@QD) biosensor has been developed for the quantitative determination of G-quadruplex and doublestranded
DNA. The ...
Determination of sunset yellow, allura red, and fast green using a novel magnetic nanoadsorbent modified with Elaeagnus angustifolia based on magnetic solid-phase extraction by HPLC
(UNIV SAO PAULO, CONJUNTO QUIMICAS, 2022)
Sunset yellow (SY), allura red (AR) and fast green (FG) are frequently used in commercial food products, although they are considered to be hazardous to public health due to their toxic efficacy and high exposure risk ...