Browsing Moleküler Biyoloji ve Genetik Bölümü Makale Koleksiyonu by Author "0000-0001-9139-1884"
Now showing items 1-6 of 6
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Antimicrobially effective protein-loaded metal chelated chitosan composite
Akkaya, Birnur; Akkaya, Recep; Taşkın Kafa Ayşe Hümeyra (Journal of Polymer Engineering, 2023)The immobilization of lysozyme onto a novel synthetic metal chelator composite based on chitosan/PAA-PMA (chitosan/acrylamide-maleic acid) and its effect on antimicrobial activity were the aim of the current study. The ... -
Chitosan-poly(acrylamide-co-maleic acid) composite synthesis, characterization, and investigation of protein adsorption behavior
Akkaya, Recep; Akkaya, Birnur; Taşkın Çakıcı Gülşen (POLYMER BULLETIN, 2023)A new environmentally friendly superabsorbent chitosan-poly(acrylamide-co-maleic acid) (chitosan/PAA-MA) was prepared by blending biocompatible chitosan and poly(acrylamide-co-maleic acid) in the polymerization medium. ... -
Doxorubucin loaded pH-responsive chitosan-poly(acrylamide-maleic acid) composite hydrogel for anticancer targeting
Akkaya, Birnur; Akkaya, Recep; Çelikkaya, Sümeyye İdil; sarıaydın, Nurgül; Raheem, K.Y. (Journal of Molecular Structure, 2023)© 2022 Elsevier B.V.A pH responsive superadsorbent composite hydrogel, chitosan-poly(acrylamide-maleic acid)(Ch-p(Ac-Ma)), were synthesized, characterized and loaded by Doxorubucin (Dox), anti-cancer drug. Chitosan solution ... -
Magnetic chitosan oligomer-sulfonate-stearic acid triple combination as cisplatin carrier for site-specific targeted on MCF-7 cancer cells: Preparation, characterization and in vitro experiments
Akkaya, Birnur; Akkaya, Recep; Nazlım, Arife (Chemical Biology and Drug Design, 2023)In this study, a new amphiphilic target-specific adsorbent, chitosan oligomer-sulfonate-stearic acid triple combination (S-Cho-SA), and magnetic chitosan oligomer-sulfonate-stearic acid triple combination (M-S-Cho-SA) by ... -
Molecular docking to investigate the inhibitory activity and the role of nitric oxide in anticonvulsant effects of vitamin D on pentylenetetrazole‑induced epileptic seizures in rats
Akkaya, Recep; Akkaya, Birnur; Bello, R. O. (Journal of Molecular Structure, 2023)© 2022 Elsevier B.V.Despite the great breakthroughs in the field of epilepsy studies, the present drugs are ineffective in one-third of the patients, as well as without providing a definite treatment. There is accumulating ... -
Preparation and characterization of lysozyme loaded cryogel for heavy metal removal
Akkaya, Birnur (International Journal of Biological Macromolecules, 2023)In the present study, monolithic poly(N-isopropylacrylamide-acrylamide)-acrilic acid (poly(npam-aam)-aac) cryogels were made. Swelling tests, SEM, XRD, and ATR-FTIR analyses revealed distinct cryogel and lysozyme-loaded ...