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dc.contributor.authorKaya, H.
dc.contributor.authorCoskun, A.
dc.contributor.authorBeton, O.
dc.contributor.authorKurt, R.
dc.contributor.authorYildirimli, M. K.
dc.contributor.authorGul, I.
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:45:10Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:45:10Z
dc.date.issued2016
dc.identifier.issn1128-3602
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7270
dc.descriptionWOS: 000382460500025en_US
dc.descriptionPubMed ID: 27424991en_US
dc.description.abstractOBJECTIVE: Carbon monoxide (CO) poisoning is very common worldwide. Despite the fact that CO is known to have cardiotoxic effects, as it has non-specific symptoms; cardiotoxicity could easily be overlooked, especially when troponin is not measured. The present study aimed to evaluate the association between troponin I levels and red cell distribution width (RDW) levels, which can be measured rapidly, easily, and afforda-bly in the Emergency Room (ER). PATIENTS AND METHODS: This single-center observational study included a total of 504 consecutive patients, who presented to the ER due to CO poisoning between January 2011 and June 2015. The diagnosis of CO poisoning was made according to the medical history and carboxyhemoglobin (COHb) level of >5%. Elevated troponin test levels, which measure >0.04 ng/ml for our laboratory, were accepted as positive. RESULTS: Patients (mean age 37 +/- 14) were classified into two groups: those who had positive troponin levels (38%) and those that did not. Patients with positive troponin, who were older, had longer CO exposure time and higher creatinine, COHb and RDW levels at the index admission following CO poisoning than patients with negative troponin. In a multivariate logistic regression model with forward stepwise method, age, COHb level, CO exposure time, and RDW (HR=1.681, 95% CI: 1.472-1.934, p<0.001) remained asso-ciated with an increased risk of troponin positivity following adjustment for the variables that were statis-tically significant in the univariate analysis and correlated with RDW. CONCLUSIONS: In patients presenting to the ER with CO poisoning, RDW can be helpful for the risk stratification of tro-ponin positivity.en_US
dc.language.isoengen_US
dc.publisherVERDUCI PUBLISHERen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarbon monoxideen_US
dc.subjectTroponinen_US
dc.subjectRed cell distribution widthen_US
dc.subjectPoisoningen_US
dc.titleA cost effective parameter for predicting the troponin elevation in patients with carbon monoxide poisoning: red cell distribution widthen_US
dc.typearticleen_US
dc.relation.journalEUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCESen_US
dc.contributor.department[Kaya, H. -- Beton, O. -- Yildirimli, M. K. -- Gul, I.] Cumhuriyet Univ, Univ Hosp, Fac Med, Heart Ctr, Sivas, Turkey -- [Coskun, A.] Sivas Numune Hosp, Dept Emergency, Sivas, Turkey -- [Kurt, R.] Sivas Numune Hosp, Dept Cardiol, Sivas, Turkeyen_US
dc.identifier.volume20en_US
dc.identifier.issue13en_US
dc.identifier.endpage2898en_US
dc.identifier.startpage2891en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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