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Primary central nervous system lymphoma in daily practice and the role of autologous stem cell transplantation in relapsed disease: A retrospective multicenter study

dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorBerber, Ilhami
dc.contributor.authorTekgunduz, Emre
dc.contributor.authorDogu, Mehmet Hilmi
dc.contributor.authorKorkmaz, Serdal
dc.contributor.authorDemir, Cengiz
dc.contributor.authorYilmaz, Mehmet
dc.contributor.authorAkay, Olga Meltem
dc.contributor.authorPala, Cigdem
dc.contributor.authorBilen, Yusuf
dc.contributor.authorKaya, Emin
dc.contributor.authorSari, Ismail
dc.contributor.authorSencan, Mehmet
dc.contributor.authorKuku, Irfan
dc.contributor.authorAltuntas, Fevzi
dc.contributor.authorDal, Mehmet Sinan
dc.contributor.authorAydogdu, Ismet
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:46:02Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:46:02Z
dc.date.issued2016
dc.identifier.issn1473-0502
dc.identifier.urihttps://dx.doi.org/10.1016/j.transci.2016.01.018
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7450
dc.descriptionWOS: 000374614700015en_US
dc.descriptionPubMed ID: 26810141en_US
dc.description.abstractWe investigated the course of 54 patients presenting with primary central nervous system lymphoma, who were treated in daily practice. The patients were treated with chemotherapy and/or radiotherapy and/or intrathecal chemotherapy. At a median follow-up period of 23 months (range 1-71), median relapse-free survival (RFS) and overall survival (OS) were not reached. Estimated 2-year RFS and OS rates were 42% and 48%, respectively. Ten relapsed PCNSL patients underwent ASCT. Complete remission rate of these patients was 40%, with 20% treatment-related mortality. Estimated 2-year RFS and OS rates were 37% and 40%, respectively. The prognosis of patients with PCNSL, who received off-study treatment, is still dismal. (c) 2016 Elsevier Ltd. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.isversionof10.1016/j.transci.2016.01.018en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutologous stem cell transplantationen_US
dc.subjectCNS lymphomaen_US
dc.subjectPCNSLen_US
dc.subjectMethotrexateen_US
dc.subjectHigh-dose chemotherapyen_US
dc.titlePrimary central nervous system lymphoma in daily practice and the role of autologous stem cell transplantation in relapsed disease: A retrospective multicenter studyen_US
dc.typearticleen_US
dc.relation.journalTRANSFUSION AND APHERESIS SCIENCEen_US
dc.contributor.department[Erkurt, Mehmet Ali -- Berber, Ilhami -- Kaya, Emin -- Kuku, Irfan] Inonu Univ, Fac Med, Dept Hematol, TR-44069 Malatya, Turkey -- [Tekgunduz, Emre -- Altuntas, Fevzi -- Dal, Mehmet Sinan] Ankara Oncol Hosp, Hematol & HCT Clin, Ankara, Turkey -- [Dogu, Mehmet Hilmi -- Sari, Ismail] Pamukkale Univ, Fac Med, Dept Hematol, Denizli, Turkey -- [Korkmaz, Serdal] Kayseri Trainer & Res Hosp, Div Hematol, Kayseri, Turkey -- [Demir, Cengiz] Yuzuncu Yil Univ, Fac Med, Dept Hematol, Van, Turkey -- [Yilmaz, Mehmet] Antep Univ, Fac Med, Dept Hematol, Gaziantep, Turkey -- [Akay, Olga Meltem] Osmangazi Univ, Fac Med, Dept Hematol, Eskisehir, Turkey -- [Pala, Cigdem] Erciyes Univ, Fac Med, Dept Hematol, Kayseri, Turkey -- [Bilen, Yusuf] Ataturk Univ, Fac Med, Dept Hematol, Erzurum, Turkey -- [Sencan, Mehmet] Cumhuriyet Univ, Fac Med, Dept Hematol, Sivas, Turkey -- [Altuntas, Fevzi] Yildirim Beyazit Univ, Fac Med, Dept Internal Med, Div Hematol, Ankara, Turkey -- [Aydogdu, Ismet] Celal Bayar Univ, Fac Med, Dept Hematol, Manisa, Turkeyen_US
dc.contributor.authorIDKAYA, Emin -- 0000-0001-8605-8497; Altuntas, Fevzi -- 0000-0001-6872-3780en_US
dc.identifier.volume54en_US
dc.identifier.issue1en_US
dc.identifier.endpage84en_US
dc.identifier.startpage80en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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