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Heat, pH Induced Aggregation and Surface Hydrophobicity of S. cerevesiae Ssa1 Protein
(SPRINGER, 2010)
Heat shock protein 70 is a conserved protein among organisms. Hsp70 helps substrate proteins to fold correctly. Unfolded substrate proteins increase the probability of the aggregate formation. High level recombinant protein ...
Tumor Targeting of Polymeric Nanoparticles Conjugated with Peptides, Saccharides, and Small Molecules for Anticancer Drugs
(BENTHAM SCIENCE PUBL LTD, 2017)
Targeting drugs or pharmaceutical compounds to tumor site increases cancer treatment efficiency and therapeutic outcome. Nanoparticles are unique delivery systems for site-targeting within an organism. Many novel technologies ...
Structure-Function Based Drug Design for Cancer Therapeutics
(BENTHAM SCIENCE PUBL LTD, 2016)
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Thematic Issue: Structural Characteristics of Short Peptides Solution Recombinant Therapeutic Protein Vaccines
(BENTHAM SCIENCE PUBL LTD, 2013)
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Heat Shock Protein 40-Gok1 Isolation from Toxoplasma gondii RH Strain
(BENTHAM SCIENCE PUBL LTD, 2013)
Toxoplasma gondii is ubiquitous obligate intracellular parasite and is one of the most important pathogen for humans and animals. In humans, T. gondii has two life forms: tachyzoites and bradyzoites. Tachyzoites form of ...
Important Anti-Cancer Applications of Protein Based Nanoparticles
(BENTHAM SCIENCE PUBL LTD, 2013)
Cancer is one of the most important health problems in the world and the treatment approaches are still challenging and generally not at desirable levels. Conventional anti-cancer agents may cause systemic toxicity, have ...
Syn, anti, and finally both conformations of cyclic AMP are involved in the CRP-dependent transcription initiation mechanism in E. coli lac operon
(JOHN WILEY & SONS LTD, 2008)
The cyclic AMP receptor protein (CRP) of Escherichia coli regulates the activity of more than 150 genes. Allosteric changes in CRP structure accompanied by cAMP binding, initiate transcription through protein binding to ...
Neglected role of cAMP receptor protein monomer
(SPRINGER, 2012)
Lac operon transcription activation through CRP dimer depends on cAMP second messenger. The formation of CRP homodimers is mediated by protein-protein interactions between the monomers. Cyclic AMP ligand binding brings CRP ...
Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic ...
Acyl Thiourea Derivatives Containing Pyrazole Ring Selective Targeting of Human Aurora Kinases in Breast and Bone Cancer
(BENTHAM SCIENCE PUBL LTD, 2015)
Several oncogenic pathways may lead to cancer. Pharmaceutical research develops efficacious compounds to inhibit these pathways. Current inhibitor drugs may block several pathways simultaneously but cause adverse and side ...